Results 41 to 50 of about 7,667 (240)

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

open access: yesMolecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto   +8 more
wiley   +1 more source

THE DECISION OF THE REPETITIVE THEME 988 OF THE STJ, TAXATIVENESS MITIGATED THE INTERLOCUTORY APPEAL AND ITS PROCEDURAL REFLEXES

open access: yesRevista Eletrônica de Direito Processual, 2020
This article has the purpose to analyze the conceptual reformulation of the interlocutory appeal by the CPC/2015, its taxativeness and restriction of hypotheses in the knowledge phase at first and, later, as object of the work and research problem ...
Vinícius da Silva Lemos
doaj   +1 more source

La adhesión a la apelación en el proceso civil peruano: nuestra propuesta a propósito del Proyecto de Reforma del Código Procesal Civil peruano

open access: yesPensar, 2022
Resumen: La presente investigación versa sobre una figura no muy novedosa al provenir de la antigua Roma, pero sí muy controversial como es la adhesión a la apelación en vista a que no existe un acuerdo paritario respecto de los límites objetivos de esta.
Arturo Saúl Grau Castillo
doaj   +1 more source

Principio de oportunidad y exclusión de la responsabilidad penal del adolescente desmovilizado del conflicto armado colombiano [PDF]

open access: yes, 2012
Este trabajo está enfocado, principalmente, a analizar los aspectos de la política criminal que regula el proceso penal de los adolescentes desmovilizados del conflicto armado, el cual se orienta con fundamento en el Principio de Oportunidad consagrado ...
Montalvo Velásquez, Cristina
core  

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Procedimientos tributarios: cuestiones polémicas

open access: yesRevista Vasca de Administración Pública, 2014
The procedural facets are becoming increasingly important when claiming the liquidations carried out by the tax office. Some of these facets deal with the delay in the tax inspector procedura, tax infringements and preclusión.
Aitor Orena Domínguez
doaj   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

Targeting p38α in cancer: challenges, opportunities, and emerging strategies

open access: yesMolecular Oncology, EarlyView.
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley   +1 more source

La acusación en Colombia

open access: yesDerecho Penal y Criminología, 2011
Para abordar los problemas de la acusación se acude a otras figuras que incluye el derecho procesal colombiano. Afirmamos que no existe una regulación específica que se relacione con el retiro de la acusación y, por tanto, debemos acudir a los mecanismos
Ángela María Buitrago Ruiz
doaj   +2 more sources

Las garantías y la tutela judicial en la etapa de indagación e investigación en el proceso penal [PDF]

open access: yes, 2013
El presente artículo analiza la problemática, que surge de la aplicación de las garantías judiciales y de la tutela judicial en la etapa de indagación e investigación en el sistema penal oral acusatorio, toda vez que no puede haber justicia o acceso a la
Castañeda Crespo, Carlos Eduardo
core   +2 more sources

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