Results 171 to 180 of about 11,588,553 (239)

When NCX switches sides: Experimental and computational insights into Ca2+ regulation in the heart

The Journal of Physiology, EarlyView.
Abstract figure legend Due to its presence inside the dyadic cleft, Na+/Ca2+ exchanger (NCX) builds a functional unit together with L‐type calcium channels and ryanodine receptors in the dyadic cleft. NCX acts bidirectionally (forward and reverse mode) dependent on extracellular calcium ([Ca2+]o) and sodium ([Na+]o) concentrations and the membrane ...
Wilhelm Neubert, Judith Hüttemeister, Paulina Sander, Nagaiah Chamakuri, Felix Hohendanner, Martin Falcke, Frank R. Heinzel   +6 more
wiley   +1 more source

AmberTorchPB: A Unified Framework for Poisson-Boltzmann-Based Reaction Field Energy Calculation via Tensor Computation. [PDF]

J Chem Theory Comput
Wu Y, Wang Q, Jiang R, Luo R.
europepmc   +1 more source

Longer action potential duration in the Purkinje network than in the ventricular myocardium delays retrograde activation of the human His‐Purkinje system

The Journal of Physiology, EarlyView.
Abstract figure legend Activation time (AT) maps from right ventricular apical pacing in a human ventricles model with longer action potential duration in the His‐Purkinje system (HPS) than in the myocardium (MYO). For pacing with a long S1S2 coupling interval (CI), the AT from the myocardial pacing site to the first AT of the HPS (ATMYO) is longer ...
Jason D. Bayer, Edward J. Vigmond, Ruben Coronel, Chantal E. Conrath   +3 more
wiley   +1 more source

Comprehensively investigating pharmacokinetics and metabolic fate of andrographolide in rats by liquid chromatography/mass spectrometry-based approach. [PDF]

RSC Adv
Sun X, Zhang Y, Shang Z, Dou L, Wang T, Qiu J, Chen S.   +6 more
europepmc   +1 more source

Computing Bounds on the Eigenvalues of the Preconditioned X‐FFT System in 3D Linear Elastic Homogenization

Proceedings in Applied Mathematics and Mechanics, Volume 26, Issue 4, December 2026.
ABSTRACT The previously introduced X‐FFT solver permits solving three‐dimensional linear elastic homogenization problems with high accuracy and efficiency. Due to the extended finite element discretization (X‐FEM), matrix‐inclusion problems may be approximated with the error convergence of interface‐conforming finite elements.
Flavia Gehrig, Matti Schneider
wiley   +1 more source

Algorithmic differentiation for plane-wave DFT: materials design, error control and learning model parameters. [PDF]

NPJ Comput Mater
Schmitz NF, Ploumhans B, Herbst MF.
europepmc   +1 more source

A Simulation Study on Spatial Exponential Decay of Perturbations in a Two‐Dimensional Wave Equation With Optimal Boundary/Line Control

Proceedings in Applied Mathematics and Mechanics, Volume 26, Issue 4, December 2026.
ABSTRACT Recent results have shown that domain‐uniform stabilizability and detectability imply spatial exponential decay of perturbations in optimally controlled hyperbolic PDEs on one‐dimensional domains. This domain‐uniform stabilizability and detectability can be achieved only if the control domain is distributed over the whole spatial domain such ...
Benedikt Oppeneiger
wiley   +1 more source

A Non-Equilibrium Thermodynamic Framework for Sequential Symmetry Breaking in Driven Complex Fluids. [PDF]

Entropy (Basel)
Miguel AF, Pepe VR, Rocha LAO.
europepmc   +1 more source

Stochastic Galerkin and Monte Carlo Methods for Parabolic Problems: Numerical Performance of Variational Matrix‐Free Approximations

Proceedings in Applied Mathematics and Mechanics, Volume 26, Issue 4, December 2026.
ABSTRACT Stochastic Galerkin methods offer unexplored potential for the numerical simulation of parabolic problems with random variables, in particular if they are combined with variational discretizations of the space and time variables. Due to the high dimensionality, the solution of the arising algebraic systems do not become feasible without ...
Moataz Dawor, Nils Margenberg, Markus Bause   +2 more
wiley   +1 more source

Mass-zero constrained molecular dynamics for electrostatic interactions. [PDF]

J Chem Phys
Troni F, Grassano D, Narayan J, Roux B, Bonella S.   +4 more
europepmc   +1 more source