Gq Signaling in Microglia Triggers Interferon Responses and Improves Outcome After Ischemic Stroke
Chemogenetic activation of Gq signaling in microglia ahead of ischemic stroke reduces infarct size in mice. Seven days after stroke, Gq‐primed microglia in the penumbra show enhanced interferon responses, altered branching patterns, and reduced phagocytosis.
Lynn Bitar +8 more
wiley +1 more source
Efficient Shift-and-Invert Preconditioning for Multi-GPU Accelerated Density Functional Calculations. [PDF]
Woo J, Youn Kim W, Choi S.
europepmc +1 more source
First‐trimester trophoblast EVs are enriched in anti‐inflammatory proteins, lipids, and immunoregulatory miRNAs. EVT‐EVs reprogram monocytes toward a pro‐resolving phenotype and restore immune homeostasis in RDEB, supporting their potential as offering a scalable off‐the‐shelf therapy for chronic inflammatory diseases.
Nell Hirt +8 more
wiley +1 more source
Polynomial Preconditioning for Indefinite Matrices
ABSTRACT Polynomial preconditioning is an important tool in solving large linear systems and eigenvalue problems. A polynomial from GMRES can be used to precondition restarted GMRES and restarted Arnoldi. Here we give methods for indefinite matrices that make polynomial preconditioning more generally applicable. The new techniques include balancing the
Hayden Henson, Ronald B. Morgan
wiley +1 more source
Um estudo da simulação da dinamica de sistemas de energia eletrica usando computadores paralelos de alto desempenho [PDF]
Azevedo, Jose Luiz Lima de
core
The Potential of Horizontal Wells for Aquifer Storage and Recovery in Saline Aquifers. [PDF]
Kreipl S, Bakker M, van Breukelen BM.
europepmc +1 more source
The Role of EVs in the Aging Hematopoietic System
Extracellular vesicles from aged bone marrow carry pro‐inflammatory cargo that drives blood stem cell decline, while youthful vesicles restore or maintain stem cell function. Circulating vesicles therefore represent both a readout of hematopoietic aging and a potential therapeutic route.
Esra G. Kosebent +5 more
wiley +1 more source
Comparison of two <sup>18</sup>F-fluorinated glycopeptides for PET imaging of the functional liver mass. [PDF]
Zierke MA +8 more
europepmc +1 more source
Testicular Biopsies in Adolescent and Adult Andrological Patients: The EAA Clinical Guidelines
ABSTRACT Background Histological evaluation of testicular tissue is central to the assessment of infertile men, particularly those at an increased risk of testicular germ cell tumors (TGCT). Traditionally, testicular biopsies have been used primarily for diagnostic purposes, such as the detection of germ cell neoplasia in situ (GCNIS). With advances in
Lise Aksglaede +11 more
wiley +1 more source
Anisotropic Lorentz force effects on the Marangoni convection in liquid metal systems for fusion applications. [PDF]
Meng X, Chen L.
europepmc +1 more source

