Results 111 to 120 of about 2,093,931 (270)

Effect of Precursors and Their Regulators on the Biosynthesis of Antibiotics in Actinomycetes

Molecules
During the life activities of microorganisms, a variety of secondary metabolites are produced, including antimicrobials and antitumor drugs, which are widely used in clinical practice.
Xu Yan, Yao Dong, Yawen Gu, Hao Cui
doaj   +1 more source

Are solar cycles predictable?

, 2007
Various methods (or recipes) have been proposed to predict future solar activity levels - with mixed success. Among these, some precursor methods based upon quantities determined around or a few years before solar minimum have provided rather high ...
Balmaceda, Brandenburg, Bushby, Cameron, Choudhuri, Dikpati, Dikpati, Echer, Harvey, Harvey, Hathaway, Hathaway, Hathaway, Lantos, Lantos, Layden, Legrand, Li, Ohl, Schatten, Schatten, Schatten, Sello, Solanki, Svalgaard, Thompson, Waldmeier, Wilson   +27 more
core   +1 more source

Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells

FEBS Open Bio, EarlyView.
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi, Zainab Quraishi, Shima Khezri Azizi Far, Madaleine Ward, Aidan Conway, Reem Abdulredha, Eman Mshari, Yousif A. Shamsaldeen   +7 more
wiley   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

FEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn, Barbara Seroka, Ryszard Lazny, Zenon Lotowski, Thore Rohwerder   +4 more
wiley   +1 more source

Constraints on the optical precursor to the naked-eye burst GRB080319B from Pi of the Sky observations

, 2012
I present the results of the search for an optical precursor to the naked-eye burst - GRB080319B, which reached 5.87m optical peak luminosity in the "Pi of the Sky" data.
Piotrowski, Lech Wiktor
core   +1 more source

Identification of functional murine mitochondrial formyl peptides and their effects on myeloid‐derived suppressor cell generation

FEBS Open Bio, EarlyView.
We first identified functional murine mitochondrial N‐formyl peptides (MT‐FPs) and investigated their effects on the in vitro myeloid‐derived suppressor cell (MDSC) generation from bone marrow cells. We demonstrated that MT‐FPs acted directly on bone marrow cells to promote MDSC generation and modulated the polymorphonuclear (PMN)‐MDSC/monocyte (M ...
Miyako Ozawa, Saori Kagoshima, Akira Yamada   +2 more
wiley   +1 more source

Preparation and Properties of C/C-(TiZrHfNbTa)C Composites via Inorganic Salt Precursor Method

C
Using low-cost transition-metal chlorides and furfuryl alcohol as raw materials, the (TiZrHfNbTa)C precursor was prepared, and a three-dimensional braided carbon fiber preform (C/C) coated with pyrolytic carbon (PyC) was used as the reinforcing material.
Haibo Ouyang, Jiyong Liu, Cuiyan Li, Tianzhan Shen, Jiaqi Liu, Mengyao He, Yanlei Li, Leer Bao   +7 more
doaj   +1 more source

YlmG1 is localized exclusively to the chloroplast envelope membrane and is involved in preprotein translocation in Arabidopsis thaliana

FEBS Open Bio, EarlyView.
Cytosolically synthesized chloroplast preproteins are translocated across the outer and inner envelope membranes through translocons called TOC and TIC, respectively. In green algae and plants, the TIC core is composed of essential membrane proteins, Tic12, Tic20, and Tic214.
Mengyi Li, Xueyang Zhao, Masato Nakai
wiley   +1 more source

Low temperature sintering process of Al2O3 ceramic

Cailiao gongcheng
In this study，alumina powder is used as the matrix material，and two organic alumina precursors with different room-temperature phases （solid-phase and liquid-phase） are selected as sintering aids，and the solid-state sintering process is adopted.
XIANG Yang, HAN Qingzhuang, MO Chen, WANG Qunbo, WEN Jin, PENG Zhihang, LIU Ping   +6 more
doaj   +1 more source

Iron homeostasis disruption and lipid peroxidation in skeletal muscle during short‐term immobilization

FEBS Open Bio, EarlyView.
14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa, Kazuhiko Higashida, Naoya Nakai   +2 more
wiley   +1 more source