Results 61 to 70 of about 2,106,963 (290)

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

DEMOCRACIA PARTICIPATIVA DESDE UNA CONCEPCIÓN TRANSMODERNA Y DESCOLONIAL

open access: yesRevista Arbitrada Interdisciplinaria Koinonía, 2018
La Constitución de la República Bolivariana de Venezuela establece el ejercicio de la democracia participativa como nueva forma de gobierno que realza la participación del pueblo como depositario único del poder, donde la representatividad desde el ...
Abg. Patricia Edén Smith Quiñones.
doaj  

Resolved shock structure of the Balmer-dominated filaments in Tycho's supernova remnant: Cosmic-ray precursor?

open access: yes, 2010
We report on the results from H{\alpha} imaging observations of the eastern limb of Tycho's supernova remnant (SN1572) using the Wide Field Planetary Camera 2 on the Hubble Space Telescope.
Ghavamian   +9 more
core   +1 more source

Transport of proteins into mitochondria [PDF]

open access: yes, 1985
Translocational intermediates of precursor proteins of ATPase F1β subunit and cytochrome c1 across mitochondrial membranes were analyzed using two different approaches, transport at low temperature and transport after binding of precursor proteins to ...
Neupert, Walter, Schleyer, Manfred
core   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Research on Mesoscale Nucleation and Growth Processes in Solution Crystallization: A Review

open access: yesCrystals, 2022
In recent studies, the existence of mesoscale precursors has been confirmed in crystallization. Different from the classical crystallization theory, which only considers the sequential attachment of basic monomers (atoms, ions, or molecules), the ...
Xiaowei Wang   +9 more
doaj   +1 more source

Assembly of the precursor and processed light-harvesting chlorophyll a/b protein of Lemna into the light-harvesting complex II of barley etiochloroplasts. [PDF]

open access: yes, 1986
When the in vitro synthesized precursor of a light-harvesting chlorophyll a/b binding protein (LHCP) from Lemna gibba is imported into barley etiochloroplasts, it is processed to a single form.
Chitnis, PR   +4 more
core   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Discovering Precursors to Tropical Cyclone Rapid Intensification in the Atlantic Basin Using Spatiotemporal Data Mining

open access: yesAtmosphere, 2022
Regarded as one of the most dangerous types of natural disaster, tropical cyclones threaten the life and health of human beings and often cause enormous economic loss.
Yun Li   +3 more
doaj   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

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