Results 91 to 100 of about 12,114 (185)
CD200/BTLA deletions in pediatric precursor B-cell acute lymphoblastic leukemia treated according to the EORTC-CLG 58951 protocol [PDF]
, 2015 DNA copy number analysis has been instrumental for the identification of genetic alterations in B-cell precursor acute lymphoblastic leukemia. Notably, some of these genetic defects have been associated with poor treatment outcome and might be relevant ...
Bakkus, Marleen +27 more
core +3 more sources
Recent Applications of Mesoporous Silica Nanoparticles in Gene Therapy
Advanced Healthcare Materials, Volume 14, Issue 26, October 7, 2025.The review summarizes the synthesis of mesoporous silica nanoparticles (MSNs) with modifiable surface properties, functionalization strategies, mechanism of therapeutic payload release, and current applications in gene therapy, focusing on their capabilities in the targeted delivery of therapeutic nucleic acids, CRISPR‐Cas systems, and other genetic ...
Tamanna Binte Huq +4 more
wiley +1 more source
대한영상의학회지, 2016 T-cell lymphoblastic lymphoma is a highly aggressive tumor derived from lymphocyte of the thymus, which accounts for 2% of non-Hodgkin's lymphoma. The disease occurs most commonly in adolescent and young adult males.
Tae Ran Ahn +4 more
doaj +1 more source
The role of micro-ribonucleic acids in normal hematopoiesis and leukemic T-lymphogenesis [PDF]
, 2010 Micro-ribonucleic acids (microRNAs) are small molecules containing 20-23 nucleotides. Despite their small size, it is likely that almost every cellular process is regulated by them.
GIMENES TEIXEIRA, H.L. +2 more
core +2 more sources
Familial Patterns in Acute Lymphoblastic Leukemia: Lessons From Three Siblings
Clinical Case Reports, Volume 13, Issue 10, October 2025.ABSTRACT Acute lymphoblastic leukemia is a sporadic condition and has been reported to be familial in less than 5% of cases. Here, we present the clinical, genetic, treatment, and pathologic features of three siblings with precursor B acute lymphoblastic leukemia by the order of occurrence, suggesting a potential involvement of germline mutations in ...
Alireza Khanahmad +3 more
wiley +1 more source
HemaSphere, Volume 9, Issue 10, October 2025.Abstract Anti‐CD19 CAR NK cells may provide a promising non‐HLA‐restricted immune cell product and have been clinically studied primarily on low‐grade B‐cell lymphoma patients. We used retroviral gene transfer to generate aCD19 CAR NK cells from the peripheral blood of healthy volunteers.
Hanna Kirchhoff +10 more
wiley +1 more source
Medical Imagery: Cytomegalovirus sialadenitis in a patient with B-cell acute lymphoblastic leukemia
IDCasesCytomegalovirus (CMV) can cause a broad range of diseases, with severity depending on immune status, comorbidities, and age. Initial CMV infection usually occurs in childhood and is typically asymptomatic, leading to lifelong latency.
Javier A. Baena-Del Valle +6 more
doaj +1 more source
Nanobody based dual specific CARs [PDF]
, 2018 Recent clinical trials have shown that adoptive chimeric antigen receptor (CAR) T cell therapy is a very potent and possibly curative option in the treatment of B cell leukemias and lymphomas.
Abken, Hinrich +8 more
core +2 more sources
Medicina, 2016 Context: Acute pancreatitis is a inflammatory process of the pancreas. It can be caused by gallstones, metabolic disorders, associated or not with alcohol abuse, or medication.
Renne Rodrigues +3 more
doaj +1 more source
Molecular mechanisms in haematological malignancies [PDF]
, 2009 Haematopoiesis requires the constant production of large numbers of peripheral blood cells. This process is under tight control of transcription factor networks as well as cytokines, growth factors and hormones.
Avellino, Roberto +2 more
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