Results 191 to 200 of about 58,276 (219)

SIRT Family: Biological Functions and Therapeutic Targets

open access: yesMedComm, Volume 7, Issue 8, August 2026.
SIRT1–SIRT7 networks from transgenic mice to human‑relevant therapeutic targets. SIRT1–SIRT7 form an isoform‑, organ‑, and disease‑specific regulatory network. Transgenic Sirt1–7 mouse models define central regulatory SIRTs (SIRT1, SIRT3, SIRT6), context‑dependent modifiers (SIRT2, SIRT4, SIRT5, SIRT7), and their key mechanisms and target organs. These
Jia‐Yi Wang   +9 more
wiley   +1 more source

Turning Cold Tumors Into Hot Tumors: Implications for Cancer Therapy

open access: yesMedComm, Volume 7, Issue 8, August 2026.
Barrier‐defined strategies for cold‐to‐hot tumor conversion. Cold tumors include immune‐desert and immune‐excluded states marked by poor antigen visibility, limited T‐cell priming, stromal or vascular exclusion, metabolic stress and suppressive immune programs.
Xiao Ge   +5 more
wiley   +1 more source

ILC imbalance - a new piece in the gut-kidney axis puzzle. [PDF]

open access: yesFront Immunol
Liu X, Fang Y, Xu Y, Wang X, Zhang W.
europepmc   +1 more source

Blood-based epigenetic instability linked to human aging and disease. [PDF]

open access: yesNat Commun
Basrai S   +14 more
europepmc   +1 more source

Enhanced Human Antigen-Specific B Cell Responses Using In Vitro 3D Tonsil Cultures Containing Stromal Cells. [PDF]

open access: yesAdv Healthc Mater
Braham MVJ   +11 more
europepmc   +1 more source

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