Results 211 to 220 of about 104,139 (265)

Targeting Inflammation and Immune Regulation in Chronic Inflammation Associated Cancers

open access: yesCancer Science, Volume 117, Issue 5, Page 1209-1222, May 2026.
Chronic inflammation sustains activation of key inflammatory pathways, including Nuclear factor kappa B (NF‐κB), Interleukin‐6‐signal transducer and activator of transcription 3 (IL6‐STAT3), Phosphoinositide 3‐kinase/Akt (PI3K/Akt), and Wingless/β‐catenin (Wnt/β‐catenin) signaling. This promotes immune dysregulation through the expansion and functional
Lawan Rabiu   +5 more
wiley   +1 more source

Whole Blood Transcriptomic Analysis of Sickle Cell Trait

open access: yesEuropean Journal of Haematology, Volume 116, Issue 5, Page 535-544, May 2026.
ABSTRACT Sickle cell trait (SCT) is the heterozygous carrier state for the HBB missense variant which causes sickle cell disease (SCD). SCT has been associated with increased risk of venous thromboembolism and chronic kidney disease as well as alterations in clinical laboratory parameters. To investigate differential gene expression in SCT, we used RNA
Mari Johnson   +12 more
wiley   +1 more source

Animal Models of Hunner‐Type Interstitial Cystitis

open access: yesInternational Journal of Urology, Volume 33, Issue 5, May 2026.
ABSTRACT Background Animal models are crucial for mechanistic studies and therapeutic development of human diseases. At present, the etiology of interstitial cystitis/bladder pain syndrome (IC/BPS), a chronic disease of the urinary bladder, remains undefined.
Yoshiyuki Akiyama, Yi Luo
wiley   +1 more source

IL-33 promotes transcriptional and metabolic adaptations of tissue-resident Th2 cells. [PDF]

open access: yesJ Immunol
Kania AK   +7 more
europepmc   +1 more source

Neuroinflammation as a result of non‐neurotropic herpesvirus infection

open access: yesImmunology &Cell Biology, Volume 104, Issue 5, Page 443-451, May‐June 2026.
Atypical memory B cells (ABCs) might stimulate autoreactive T cells to cause neuroinflammation and CNS myeloid cell activation during MS. Abstract The non‐neurotropic Epstein Barr virus (EBV) has been suggested to initiate the prodromal phase of multiple sclerosis (MS), often years before the first clinical symptoms. This review discusses mechanisms by
Christian Münz
wiley   +1 more source

Lymphocytosis and Mycobacteriosis in a 15-Year-Old Mixed-Breed Dog. [PDF]

open access: yesCase Rep Vet Med
Murphy BJ   +3 more
europepmc   +1 more source

Emerging mechanisms of ILC2‐neuronal crosstalk across the body

open access: yesImmunology &Cell Biology, Volume 104, Issue 5, Page 439-442, May‐June 2026.
Emerging roles of ILC2 in neuronal crosstalk across organs. In a series of studies published in 2025, ILC2 were shown to regulate nervous system function across a range of organs across the body. Within the intestinal tract, ILC2‐derived cytokines acted on enteric neurons to orchestrate immunity to helminths (Wang et al).
David A Posner, Matthew R Hepworth
wiley   +1 more source

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