Results 81 to 90 of about 50,528 (188)

Organoids in Haematologic Research: Advances and Future Directions

Cell Proliferation, EarlyView.
This review focuses on the advancements in organoid technology and its transformative role in haematological research, particularly in the modelling of haematopoietic tissues, blood diseases and drug development. It also offers an outlook on the future prospects of organoids in personalised medicine and the study of disease mechanisms.
Liangzheng Chang, Lu Li, Yuling Han, Hui Cheng, Liuliu Yang   +4 more
wiley   +1 more source

Proposal for a New Classification of Rare Cancers Adopting Updated Histological Tumor Types

Pathology International, EarlyView.
We propose a new rare cancer classification system using the updated International Classification of Diseases for Oncology 3.2 coding system and the World Health Organization Classification of Tumors 5th edition. This list could serve as a diagnostic classifier to reliably distinguish various rare cancers for clinical applications.
Ryoko Rikitake, Yasushi Yatabe, Yoko Yamamoto, Tatsunori Shimoi, Shintaro Iwata, Yasushi Goto, Yu Mizushima, Akira Kawai, Takahiro Higashi   +8 more
wiley   +1 more source

Generating counterfactual explanations of tumor spatial proteomes to discover effective strategies for enhancing immune infiltration [PDF]

arXiv, 2022
The tumor microenvironment (TME) significantly impacts cancer prognosis due to its immune composition. While therapies for altering the immune composition, including immunotherapies, have shown exciting results for treating hematological cancers, they are less effective for immunologically-cold, solid tumors.
arxiv  

Childhood Lymphoblastic Lymphoma: Hospital Based Study.

مجلة كلية الطب, 2015
Background: Lymphoblastic lymphomas (LBL) are neoplasms of precursor T cells and B cells, or lymphoblasts. The term lymphoblastic lymphoma has been used to describe predominantly lymph node– based disease; however, clinical distinction between LBL and ...
Samaher A. Fadhil, Amir F. Al-Darraji, Raghad M. Al-saeed, Salma Al-Hadad   +3 more
doaj   +1 more source

Impacts of Vincristine and Prednisolone Chemotherapy on the Canine Gut Microbiota in Dogs Undergoing Treatment for Lymphoma

Veterinary and Comparative Oncology, EarlyView.
ABSTRACT Chemotherapy can have adverse gastrointestinal effects in dogs and people. The objective of this study was to assess the impact of vincristine and prednisolone/prednisone, as part of a CHOP chemotherapy [cyclophosphamide, hydroxydaunorubicin, oncovin (vincristine) and prednisolone/prednisone] protocol, on gastrointestinal dysbiosis in dogs ...
Juan Aragon, Annika M. Weber, Madison Tipton, Jennifer Thomsen, Hend Ibrahim, Kristen Weishaar, Sangeeta Rao, Jan S. Suchodolski, Jonathan Stockman, Elizabeth P. Ryan, Nora Jean Nealon   +10 more
wiley   +1 more source

Diagnosis and Classification of Primary Nodal Lymphomas in Dogs: A Consensus of the Oncology‐Pathology Working Group

Veterinary and Comparative Oncology, EarlyView.
ABSTRACT One of the primary objectives of the Oncology Pathology Working Group (OPWG) is for oncologists and pathologists to collaboratively generate consensus documents to standardise aspects of and provide guidelines for oncologic pathology in veterinary species.
Michael O. Childress, Anne Avery, Erica Behling‐Kelly, Peter Bennett, Laura Brockley, Ryan Dickinson, Kelly Hughes, William C. Kisseberth, Laura Marconato, Valeria Martini, Angela McCleary‐Wheeler, Lucia Minoli, Peter Rowland, Shane Sills, Luca Aresu   +14 more
wiley   +1 more source

Pediatric lymphoma may develop by "one-step" cell transformation of a lymphoid cell [PDF]

arXiv, 2018
Lymphomas are a large group of neoplasms developed from lymphoid cells (LCs) in lymph nodes (LNs) or lymphoid tissues (LTs). Some forms of lymphomas, including Burkitt lymphoma (BL), ALK+ anaplastic large cell lymphoma (ALK+-ALCL), and T-cell lymphoblastic lymphoma/leukemia (T-LBL), occur mainly in children and teenagers.
arxiv  

Multi‐Target Drug Design in Alzheimer's Disease Treatment: Emerging Technologies, Advantages, Challenges, and Limitations

Pharmacology Research &Perspectives, Volume 13, Issue 4, August 2025.
ABSTRACT Alzheimer's disease (AD) is a complex and multifactorial neurodegenerative disorder, recognized as the most prevalent form of dementia. It is characterized by multiple pathological processes, including amyloid‐beta accumulation, neurofibrillary tangles, and neuroinflammation. The therapeutic efficacy of traditional single‐target drugs has been
Md Saad Hossain, Md Hamed Hussain
wiley   +1 more source

Precursor T-cell acute lymphoblastic leukemia presenting with bone marrow necrosis: a case report

Journal of Medical Case Reports, 2012
Introduction Bone marrow necrosis is a clinicopathological condition diagnosed most often at postmortem examination, but it is also seen during the course of malignancy and is not always associated with a poor prognosis.
Khoshnaw Najmaddin SH, Al-Rawi Hisham A, Nore Beston F   +2 more
doaj   +1 more source

Petri-net modeling of B-cell receptor signaling pathways: A case study in CLL [PDF]

arXiv, 2019
Immunology is the emerging research area which deals with the study of the immune system in any living organism. It is modelled through various computational and mathematical models to deal with the problem facing while to boost the immune system of an organism or to fight with the infectious disease at the very initial stage.
arxiv