Results 71 to 80 of about 31,911 (153)

Efficacy evaluation of the 2017 protocol by the China Net Childhood Lymphoma in treating early T cell precursors-lymphoblastic lymphoma in pediatric patients

Cancer Treatment and Research Communications
To analyze the clinical features of early T-cell precursor acute lymphoblastic leukemia/lymphoma (ETP-ALL/LBL) in pediatric patients and to summarize the efficacy evaluation of the 2017 protocol by the China Net Childhood Lymphoma (CNCL) Non-Hodgkin ...
Huang Zhizhuo, Jin Ling, Liu Wei, Sun Lirong, Zhang Baoxi, Zhuang Shuquan, Yuan Xiaojun, Jia Yueping, Zhang Yonghong   +8 more
doaj   +1 more source

Acute Lymphoblastic Leukemia in Infants: 20 years of Experience

Jornal de Pediatria, 2013
Objective: To analyze patients younger than 2 years with acute lymphoblastic leukemia, treated in the period between 1990 and 2010 in a state reference center.
Amanda Ibagy, Denise B. Silva, Jackline Seiben, Ana P.F.F. Winneshoffer, Tatiana E.J.B. Costa, Juliana S. Dacoregio, Imaruí Costa, Daniel Faraco   +7 more
doaj   +1 more source

Clinical Insights Into Hypercalcemia of Malignancy in Childhood

Pediatric Blood &Cancer, Volume 73, Issue 7, July 2026.
ABSTRACT Hypercalcemia of malignancy (HCM) is a rare but life‐threatening metabolic emergency in children that occurs in less than 1% of pediatric cancer cases, with a reported incidence ranging from 0.4% to 1.0% across different studies. While it is observed in 10%–20% of adult malignancies, pediatric HCM remains relatively uncommon.
Hüseyin Anıl Korkmaz
wiley   +1 more source

Two Faces of NOTCH1 in Childhood Lymphoblastic T‐Cell Neoplasia: Prognostic Divergence of Mutational and Structural Aberrations

Pediatric Blood &Cancer, Volume 73, Issue 7, July 2026.
ABSTRACT In pediatric patients, T‐cell lymphoblastic lymphoma (T‐LBL) survival exceeds 80%. Relapse remains associated with limited curative options. Frontline treatment is largely extrapolated from T‐cell acute lymphoblastic leukemia (T‐ALL) treatment, reflecting the ongoing debate, whether both entities represent distinct diseases or variants within ...
Marie C. Heider, Amelie Alfert, Marc Hotfilder, Birgit Burkardt, Marcel te Vrugt   +4 more
wiley   +1 more source

Precursor T-cell acute lymphoblastic leukemia presenting with bone marrow necrosis: a case report

Journal of Medical Case Reports, 2012
Introduction Bone marrow necrosis is a clinicopathological condition diagnosed most often at postmortem examination, but it is also seen during the course of malignancy and is not always associated with a poor prognosis.
Khoshnaw Najmaddin SH, Al-Rawi Hisham A, Nore Beston F   +2 more
doaj   +1 more source

Acute Lymphoblastic Leukemia Presenting With Severe Acute Kidney Injury Requiring Hemodialysis due to Kidney Infiltration: A Case Report

Clinical Case Reports, Volume 14, Issue 7, July 2026.
ABSTRACT A 66‐year‐old man presented with dialysis‐dependent acute kidney injury without cytopenia or peripheral blasts. Kidney biopsy revealed leukemic infiltration and led to the diagnosis of Philadelphia chromosome‐negative B‐acute lymphoblastic leukemia.
Semin Cho, Soyean Kwon, Jeong Hwan Park, Jin Hyun Park, Ki Hwan Kim, Jin Soo Kim, Eun Youn Roh, In Sil Choi, Ji Eun Kim, Song Yi Park   +9 more
wiley   +1 more source

SET-NUP214 Fusion Gene Involved Early T-Cell Precursor Acute Lymphoblastic Leukemia in Adult with B Marker Expression

International Journal of General Medicine, 2021
Xiaoying Xu,1 Qiongli Zhai,1 Hao Jin,2 Yong Yu,3 Dongmei Han,2 Huilai Zhang,4 Kai Fu,5 Bin Meng1 1Department of Pathology, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Key Laboratory of Cancer ...
Xu X, Zhai Q, Jin H, Yu Y, Han D, Zhang H, Fu K, Meng B   +7 more
doaj  

Study of T-cell immunoglobulin and mucin domain-3 expression profile in peripheral blood and bone marrow of human acute lymphoblastic leukemia patients

Journal of Research in Medical Sciences, 2020
Background: Acute lymphoblastic leukemia (ALL) is a malignancy with aggressive tumors of immature lymphocytes. T-cell immunoglobulin and mucin-domain 3 (TIM-3) is a Type I transmembrane glycoprotein which is involved in cell proliferation.
Narges Zargar Balajam, Mahdi Shabani, Mahmoud Aghaei, Mansoureh Haghighi, Farzad Kompani   +4 more
doaj   +1 more source

High IL‐10 levels during CRS are negatively associated with NK‐cell recovery after CAR‐T cell therapy

Clinical &Translational Immunology, Volume 15, Issue 7, 2026.
This study demonstrates that high IL‐10 levels during cytokine release syndrome significantly delay natural killer (NK)‐cell recovery after CD19 CAR‐T cell therapy, increasing viral infection risks. Mechanistically, IL‐10 impairs NK‐cell recovery by promoting apoptosis and ferroptosis, suggesting that targeting IL‐10 or employing anti‐inflammatory ...
Xindi Wang, Wenjing Luo, Yingying Li, Jianghua Wu, Lu Tang, Chenggong Li, Qiaolin Liu, Zhihan Chen, Yu Hu, Heng Mei   +9 more
wiley   +1 more source

Frequency and clinical relevance of DNA microsatellite alterations of the CDKN2A/B, ATM and p53 gene loci: a comparison between pediatric precursor T-cell lymphoblastic lymphoma and T-cell lymphoblastic leukemia

Haematologica, 2010
Although deletions of cell cycle regulatory gene loci have long been reported in various malignancies, little is known regarding their relevance in pediatric T-cell lymphoblastic lymphoma (T-LBL) and T-cell lymphoblastic leukemia (TALL).
David Krieger, Anja Moericke, Ilske Oschlies, Martin Zimmermann, Martin Schrappe, Alfred Reiter, Birgit Burkhardt   +6 more
doaj   +1 more source