Results 51 to 60 of about 43,043 (156)

The status of cell and gene therapy education in medical schools—An international survey

Transfusion, EarlyView.
Abstract Introduction Cell and gene therapy (CGT) has emerged as a distinct medical field with more than 50 “Food and Drug Administration (FDA)”‐approved products treating conditions from leukemia to sickle cell disease. Despite this therapeutic revolution and the field's inherent complexity, the status of CGT education in medical schools remains ...
Edina A. Wappler‐Guzzetta, Alexandra M. Tabacu, Elena Nedelcu   +2 more
wiley   +1 more source

Feature selection for microarray gene expression data using simulated annealing guided by the multivariate joint entropy [PDF]

, 2013
In this work a new way to calculate the multivariate joint entropy is presented. This measure is the basis for a fast information-theoretic based evaluation of gene relevance in a Microarray Gene Expression data context.
Belanche Muñoz, Luis Antonio, González Navarro, Félix Fernando   +1 more
core   +5 more sources

Aosta Valley animal cancer registry: A collaborative initiative for monitoring cancer burden in animals

Veterinary Record Open, Volume 13, Issue 1, June 2026.
Abstract Background Animal cancer registry data are important for monitoring animal health, for prevention and research in veterinary medicine, and for comparative oncology. Since people and animals share the same environment and are exposed to many common risk factors, cancer patterns in animals may have a sentinel function for human health.
Claudio Trentin, Giulio Barigelletti, Caterina Abate, Giovanna Michela Villa, Emilio Bazzocchi, Lorenzo Domenis, Silvia Vuillermoz, Magda Giulia Santini, Barbara Avuzzi, Alessandro Borgini, Giovanna Tagliabue   +10 more
wiley   +1 more source

Residential exposure to solar ultraviolet radiation and incidence of childhood hematological malignancies in France [PDF]

, 2015
Few studies have investigated the relationship between solar ultraviolet radiation (UV) and childhood hematological malignancies (CHM). This study addresses the associations between residential UV exposure at diagnosis and the incidence of types and ...
Boniol, Mathieu, Clavel, Jacqueline, Coste, Astrid, Doré, Jean-François, Faure, Laure, Goujon, Stéphanie, Hémon, Denis, Marquant, Fabienne   +7 more
core   +3 more sources

The Contribution to the Assignment of Defined Daily Dose (DDD) to Antineoplastic Drugs of the Italian Working Group on DDD

Pharmacoepidemiology and Drug Safety, Volume 35, Issue 5, May 2026.
ABSTRACT Purpose To report the experience of the Italian Working Group on DDD (Ita‐DDD‐wg) in assigning DDDs to a list of antineoplastic agents. Methods Active substances from the ATC L01 group with no assigned DDD and reimbursed at least once during 2021 by the Italian Healthcare Service were identified.
Angela Boccia, Giulia Hyeraci, Anna Girardi, Rosa Gini, Gianluca Trifirò, Ylenia Ingrasciotta, Andrea Spini, Valentina Ientile, Elisabetta Poluzzi, Giampiero Mazzaglia, Ippazio Cosimo Antonazzo, Casula Manuela, Elena Tragni, Olivia Leoni, Arianna Mazzone, Michele Ercolanoni, Martina Zanforlini, Ursula Kirchmayer, Belleudi Valeria, Marco Finocchietti, Francesco Barone‐Adesi, Giuseppe Roberto   +21 more
wiley   +1 more source

ZEB2 and LMO2 drive immature T-cell lymphoblastic leukemia via distinct oncogenic mechanisms [PDF]

, 2019
ZEB1 and ZEB2 are structurally related E-box binding homeobox transcription factors that induce epithelial to mesenchymal transitions during development and disease.
Berx, Geert, Curtis, David J, De Medts, Jelle, Goossens, Steven, Haigh, Jody J, Haigh, Katharina, Nguyen, Thao, Saw, Jesslyn, T'Sas, Sara, Taghon, Tom, Tremblay, Cedric, Van Vlierberghe, Pieter, Wang, Jueqiong   +12 more
core   +3 more sources

Isolated Central Nervous System Presentation of Early T‐Cell Precursor Acute Lymphoblastic Leukemia/Lymphoma: A Rare Case of Exclusive Brain Involvement

Case Reports in Hematology
Early T‐cell precursor acute lymphoblastic leukemia/lymphoma (ETP‐ALL/LBL) is a high‐risk and biologically distinct subset of T‐cell acute lymphoblastic leukemia, typically characterized by leukemic involvement of bone marrow, peripheral blood, and mediastinal structures.
Violet O. Swart, Behyar Zoghi
openaire   +2 more sources

Clinical Characteristics and Prognostic Risk Factors for Pediatric B‐Cell Lymphoblastic Lymphoma: A Multicenter Retrospective Cohort Study for China Net Childhood Lymphoma

Pediatric Blood &Cancer, Volume 73, Issue 4, April 2026.
ABSTRACT Background B‐cell lymphoblastic lymphoma (B‐LBL) represents a rare variety of non‐Hodgkin lymphoma, with limited research on its biology, progression, and management. Methods A retrospective analysis was performed on the clinical characteristics of 256 patients aged ≤18 years who received treatment under the China Net Childhood Lymphoma (CNCL)‐
Zhijuan Liu, Jian Wang, Ling Jin, Yanlong Duan, Fu Li, Yueping Jia, Leping Zhang, Xiaojun Yuan, Wei Liu, Ying Liu, Ansheng Liu, Mincui Zheng, Yunpeng Dai, Lian Jiang, Lirong Sun, Xiaowen Zhai, Rong Liu, Chunju Zhou, Zifen Gao, Yonghong Zhang, Xiaomei Yang   +20 more
wiley   +1 more source

Consensus definitions of 14 severe acute toxic effects for childhood lymphoblastic leukaemia treatment: a Delphi consensus [PDF]

, 2016
Although there are high survival rates for children with acute lymphoblastic leukaemia, their outcome is often counterbalanced by the burden of toxic effects.
Attarbaschi, Andishe, Barzilai, Shlomit, Escherich, Gabriele, Frandsen, Thomas Leth, Halsey, Christina, Hough, Rachael, Jeha, Sima, Kato, Motohiro, Liang, Der-Cherng, Mikkelsen, Torben Stamm, Moricke, Anja, Niinimaki, Riitta, Piette, Caroline, Putti, Maria Caterina, Raetz, Elizabeth, Schmiegelow, Kjeld, Silverman, Lewis B., Skinner, Roderick, Tuckuviene, Ruta, van der Sluis, Inge, Zapotocka, Ester   +20 more
core   +2 more sources

Capacitance Technology Enables Automated Feeding, Improved Expansion, and Higher Throughput of CAR‐T Cell Stirred‐Tank Bioreactor Cultures

Biotechnology Journal, Volume 21, Issue 4, April 2026.
Graphical Abstract and Lay Summary This article demonstrates how capacitance probes can be applied to single‐patient (autologous) manufacturing processes within the cell and gene therapy (CGT) industry by using CAR‐T cells as a case study. Current CGT processes require operator intervention to sample, monitor and harvest each batch which increases ...
Ivano Luigi Colao, Jacob Cunningham, Matthew Lee, Stephen Goldrick, Qasim Ali Rafiq   +4 more
wiley   +1 more source