Results 41 to 50 of about 346,710 (306)

Sexual Selection and the Treatment of Predecessors’ Progeny by Replacement Mates

Frontiers in Psychology, 2022
Darwin’s theory of sexual selection provides a useful framework for understanding the behavior of stepparents. A non-human animal whose new mate has dependent young may kill, ignore, or adopt the predecessor’s progeny.
Martin Daly, Gretchen Perry
doaj   +1 more source

Hypothesis Testing in Feedforward Networks with Broadcast Failures

, 2013
Consider a countably infinite set of nodes, which sequentially make decisions between two given hypotheses. Each node takes a measurement of the underlying truth, observes the decisions from some immediate predecessors, and makes a decision between the ...
Chong, Edwin K. P., Moran, William, Pezeshki, Ali, Zhang, Zhenliang   +3 more
core   +1 more source

Population screening for colorectal cancer means getting FIT:the past, present, and future of colorectal cancer screening using the fecal immunochemical test for hemoglobin (FIT) [PDF]

, 2014
Fecal immunochemical tests for hemoglobin (FIT) are changing the manner in which colorectal cancer (CRC) is screened. Although these tests are being performed worldwide, why is this test different from its predecessors?
Ahlquist, Allison, Allison, Allison, Allison, Atkin, Barrows, Brenner, Burtonwood, Callum G. Fraser, Center, Cole, Cole, Cole, Cole, Crotta, Denters, Digby, Fleisher, Fletcher, Fraser, Fraser, Fraser, Fraser, Fraser, Graeme P. Young, Grazzini, Halloran, Hardcastle, Hewitson, Hoff, Hol, Imperiale, Imperiale, James E. Allison, Jemal, Jemal, Khalid-de Bakker, Kronborg, Levi, Levi, Levin, Mandel, Morikawa, Niv, Osborn, Park, Petrelli, Potter, Potter, Potter, Potter, Potter, Qaseem, Quintero, Raginel, Robinson, Rozen, Saito, Saito, Schoen, Segnan, Segnan, Shaukat, Shimbo, Simon, Songster, Songster, St John, Steele, Steele, Stegeman, Stephen P. Halloran, Sugerman, Tao, van Roon, van Roon, van Roon, van Rossum, Vart, Vellacott, Ventura, Walsh, Williams, Young, Zajac, Zauber   +86 more
core   +3 more sources

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Like John Major before him, David Cameron has pragmaticallymanaged his party’s dissensions over Europe withoutaddressing their fundamental sources. [PDF]

, 2012
Much as it did for his predecessors in the 1980s and 1990s, the “Europe Problem” has caused headaches for UK Prime Minister, David Cameron. While some have commented that Cameron has been more flexible on these issues than some of his predecessors, Simon
Usherwood, Simon
core  

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Efficient winter wheat cultivation in high-productivity different-field crop rotations under the conditions of unstable moisture in the Forest-Steppe zone of Ukraine

Наукові доповіді Національного університету біоресурсів і природокористування України
The application of modern technologies for cultivating winter wheat in scientifically grounded crop rotations is increasingly important in the context of climate change.
P. Boiko, O. Demydenko, I. Shapoval, N. Kovalenko   +3 more
doaj   +1 more source

Small colorectal polyps as predecessors of colorectal cancer

Клінічна хірургія, 2018
Objective. Аnalysis of pathohistological structure of small polyps (up to 5 mm in size), revealed while doing colonoscopy, and estimation of their transformation into malignant tumors. Маterials and methods.
А. К. Safiyeva, N. Yu. Bayramov
doaj   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source