Results 61 to 70 of about 346,710 (306)

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

PREDECESSORS AND PERPETRATORS OF COOPERATIVE SYSTEMS IN EUROPE [PDF]

Challenges of the Knowledge Society, 2013
The study hereby aims to bring forward afresh the cooperative ideas that have animated particularly the last two centuries of the past millennium. In the present context, labelled by the major difficulties the European labour market is facing, the proper
ŞTEFAN NAUBAUER
doaj  

Predecessors of Contemporary Russian õ in the Toponymy of Ingermanland; 211-217 [PDF]

Linguistica Uralica, 2007
On the ground of certain conservatism in Finnic adaptations of imported Slavic place-names some reconstructions are presented of possible Slavic place-names of Ingermanland dated back to times before the first Slavic palatalization of velars (Finnish ...
Nikolai Kirsanov
doaj   +1 more source

Contourograph display system for monitoring electrocardiograms [PDF]

, 1970
Electrocardiogram is displayed as a contourogram on the cathode ray tube of a variable-persistence oscilloscope. Each cycle is stacked below its predecessors giving a three dimensional effect.
Golden, D. P., Jr., Maudlin, D. G., Wolthuis, R. A.   +2 more
core   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Taysīr al-Qirāʾāt al-Qurʾāniyyah fī Sulṭanat Brunāy Dār al-Salām

Al-Zahra: Journal for Islamic and Arabic Studies
In the current era, many students encounter challenges in understanding the science of Qur'anic readings due to the complexity of its terms, symbols, methods, and narrations. This has led to a noticeable preoccupation with the subject, impacting both the
Saeed Abdullah Saeed Al-Khateri, Ahmad Baha Bin Haji Mokhtar, Khairun Naqibah binti Haji Lazim   +2 more
doaj   +1 more source

Seneca’s philosophical predecessors and contemporaries [PDF]

, 2013
This new and important introduction to Seneca provides a systematic and concise presentation of this author’s philosophical works and his tragedies.
Sellars, John
core  

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

DIE UNIFORM KNOPE VAN DIE SUID-AFRIKAANSE VLOOT EN SY VOORGANGERS

Scientia Militaria, 2012
No article has previously been written on the buttons of the SA Navy and its predecessors. As a complete history of these buttons will necessitate interviews with a considerable number of pensioned naval personnel and the sources of the SADF Archives ...
W. Bisset
doaj   +1 more source