Results 71 to 80 of about 346,710 (306)

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

NH Residents Positive About Sununu, Legislature, State Outlook 2/15/17 [PDF]

open access: yes, 2017
Newly-elected Governor Chris Sununu\u27s job approval is consistent with those of his predecessors at the outset of their governorships, and his personal favorability has risen considerably since the 2016 campaign.
Survey Center, UNH
core   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

Predecessor machines

open access: yesJournal of Computer and System Sciences, 1974
A predecessor machine is a random-access machine with a predecessor operation (i.e., an instruction which subtracts 1 from the contents of a memory cell), but with no operation which can increase the contents of a cell. A regressing function is a partial function which never yields an output larger than the maximum of its inputs and a constant.
Fischer, Patrick C., Warkentin, John C.
openaire   +1 more source

Molecular cancer prevention: Intercepting disease

open access: yesMolecular Oncology, EarlyView.
Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco   +2 more
wiley   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

open access: yesMolecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel   +12 more
wiley   +1 more source

Adaptive technology of sweet sorghum (Sorghum Moench.) cultivation in the Republic of Mordovia

open access: yesАграрная наука Евро-Северо-Востока, 2016
For the conditions of the Republic of Mordovia adaptive technology of cultivation of sweet sorghum is developed which is based on resource-saving techniques to ensure the creation of high-productive agro-cenoses.
A. A. Artemyev, I. P. Tarakin
doaj  

Can You Believe Your Neighbors' Behaviors? [PDF]

open access: yes
In the theoretical assumption of informational cascades, private signals and predecessors' actions are equivalently informative before informational cascades, but are not once informational cascades have started.
Shunichiro Sasaki, Toshiji Kawagoe
core  

A Marketing Booklet for Brotherwood Decoration: a Way to Promote This New Company and Its Products to Its Prospective Customers [PDF]

open access: yes, 2015
Brotherwood Decoration is a new decoration company based in Surabaya which uses recycled wood as the main material. This Company was just recently established in June 2014.
Gunawan, S. (Samuel)   +1 more
core  

Microglial dynamics and ferroptosis induction in human iPSC‐derived neuron–astrocyte–microglia tri‐cultures

open access: yesFEBS Open Bio, EarlyView.
A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li   +6 more
wiley   +1 more source

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