Exploration of Medicine, 2022 Aim: Lactate dehydrogenase (LDH) is an enzyme that acts as a catalyst in the conversion of lactate to pyruvate which is abundantly found in liver, kidney, heart and muscles.
Charu Mishra +6 more
doaj +1 more source
Increased risk of cancer and cancer-related mortality in middle-aged Korean women with prediabetes and diabetes: a population-based study [PDF]
Epidemiology and Health, 2023 OBJECTIVES This study investigated the risk of developing and dying from all types of cancer, as well as cancer-specific mortality, in women diagnosed with prediabetes and diabetes.
Thi Xuan Mai Tran +3 more
doaj +1 more source
Association of metabolic dysregulation with volumetric brain magnetic resonance imaging and cognitive markers of subclinical brain aging in middle-aged adults: the Framingham Offspring Study. [PDF]
, 2011 ObjectiveDiabetic and prediabtic states, including insulin resistance, fasting hyperglycemia, and hyperinsulinemia, are associated with metabolic dysregulation.
Au, Rhoda +9 more
core +5 more sources
Uric acid is more strongly associated with impaired glucose regulation in women than in men from the general population: the KORA F4-Study. [PDF]
, 2012 High serum uric acid (UA) levels are associated with the metabolic syndrome, type 2 diabetes and cardiovascular disease. It is largely unknown whether there are gender-specific differences regarding the association between UA and prediabetic states.
Döring, Angela +5 more
core +7 more sources
Amyloid beta and diabetic pathology cooperatively stimulate cytokine expression in an Alzheimer's mouse model [PDF]
, 2020 Background Diabetes is a risk factor for developing Alzheimer's disease (AD); however, the mechanism by which diabetes can promote AD pathology remains unknown.
Fernández Ponce, Cecilia Matilde +7 more
core +3 more sources
Hemoglobin A1c Levels Modify Associations between Dietary Acid Load and Breast Cancer Recurrence. [PDF]
, 2020 BackgroundMetabolic acidosis promotes cancer metastasis. No prospective studies have examined the association between dietary acid load and breast cancer recurrence among breast cancer survivors, who are susceptible to metabolic acidosis.
Hsu, Fang-Chi +4 more
core +2 more sources
Periodontology 2000, EarlyView., 2023 Abstract This review describes the origin and results of the prospective longitudinal study to test potential prognostic indicators for periodontal breakdown in a population deprived of regular dental care. Experimental gingivitis studies in individuals highly susceptible or highly resistant to periodontitis showed that bleeding on probing developed ...
Ubele Van der Velden
wiley +1 more source
Elevated cystatin-C concentration is associated with progression to prediabetes: the Western New York Study [PDF]
, 2007 OBJECTIVE – We conducted a nested case-control investigation to examine if elevated baseline concentrations of cystatin-C predicted progression from normoglycaemia to prediabetes over 6 years of follow-up from the Western New York Health Study. RESEARCH
Dmochowski, Jacek +5 more
core +1 more source
Canadian Journal of Gastroenterology and Hepatology, 2020 Background. Prediabetes is an intermediary hyperglycaemic state that precedes type 2 diabetes mellitus (T2DM) in which abnormal metabolism of glucose and lipids occurs in organs such as the liver.
Akinjide Moses Akinnuga +5 more
doaj +1 more source
Plasma Adiponectin Levels in Elderly Patients with Prediabetes [PDF]
Endocrinology and Metabolism, 2015 BackgroundThe significance of adiponectin levels in elderly individuals with prediabetes has yet to be determined. Thus, the present study was performed to evaluate the relationships between adiponectin levels and anthropometric variables, body ...
Si Eun Kong +5 more
doaj +1 more source