Results 51 to 60 of about 28,969 (227)

Early sensory neurophysiological changes in prediabetes

open access: yesJournal of Diabetes Investigation, 2020
Aims/Introduction To elucidate whether axonal changes arise in the prediabetic state and to find a biomarker for early detection of neurophysiological changes.
Yi‐Chen Lin   +6 more
doaj   +1 more source

Modulation and bioinformatics screening of hepatic mRNA-lncRNAs (HML) network associated with insulin resistance in prediabetic and exercised mice

open access: yesNutrition & Metabolism, 2021
Background Insulin resistance is associated with prediabetes and further progression to type 2 diabetes mellitus (T2DM). This study aims to investigate novel hepatic lncRNAs associated with key genes in insulin resistance in prediabetes.
Fatemeh Kazeminasab   +4 more
doaj   +1 more source

糖尿病和非糖尿病患者腹部皮下和内脏脂肪组织神经酰胺的变化

open access: yesJournal of Diabetes, 2022
Background This study profiles ceramides extracted from visceral and subcutaneous adipose tissue of human subjects by liquid chromatography‐mass spectrometry to determine a correlation with status of diabetes and gender.
Michelle Brusatori   +7 more
doaj   +1 more source

Childhood Maltreatment Is an Independent Risk Factor for Prediabetic Disturbances in Glucose Regulation

open access: yesFrontiers in Endocrinology, 2017
AimsChildhood maltreatment (CM) is shown to be associated with obesity and depression. However, the relationship of CM to prediabetic state is much less studied.
Li Li   +2 more
doaj   +1 more source

Decoding the Pathophysiology of Autoimmune Diseases—Mechanism, Triggers, and Nanotherapeutics: A Review

open access: yesAdvanced NanoBiomed Research, EarlyView.
This review highlights how autoimmune diseases arise from intertwined immunological, genetic, and environmental factors, emphasizing gut microbiota dysbiosis as a pivotal driver. It outlines emerging nanotechnology‐based strategies—such as liposomes, hydrogels, and polymeric nanoparticles—that enhance targeted drug delivery, minimize systemic toxicity,
Md. Meraj Ansari   +5 more
wiley   +1 more source

Chronic Microvascular Complications in Prediabetic States—An Overview [PDF]

open access: yesJournal of Clinical Medicine, 2020
A prediabetic state is a major risk factor for the development of diabetes, and, because of an identical pathophysiological background of both conditions, their prevalence increases parallelly and equally fast. Long-term hyperglycemia is the main cause inducing chronic complications of diabetes, yet the range of glucose levels at which they start has ...
Angelika Baranowska-Jurkun   +2 more
openaire   +2 more sources

Established and emerging biomarkers for the prediction of type 1 diabetes: a systematic review [PDF]

open access: yes, 2014
Type 1 diabetes (T1D) is an autoimmune disease with a prolonged and variable latent period that culminates in the destruction of pancreatic β-cells and the development of hyperglycemia.
BLUM, JANICE S.   +3 more
core   +1 more source

GLP‐1 agonists and the gut microbiome: A bidirectional relationship

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Glucagon‐like peptide‐1 (GLP‐1) receptor agonists have transformed the management of type 2 diabetes mellitus (T2DM) and obesity, yet their interactions with the gut microbiome remain an emerging frontier in pharmacological and metabolic research.
Srinivas Kamath   +2 more
wiley   +1 more source

Myocardial Perfusion and Function Are Distinctly Altered by Sevoflurane Anesthesia in Diet-Induced Prediabetic Rats

open access: yesJournal of Diabetes Research, 2016
Preservation of myocardial perfusion during surgery is particularly important in patients with increased risk for perioperative complications, such as diabetes.
Charissa E. van den Brom   +7 more
doaj   +1 more source

Ryanodine receptor phosphorylation by CaMKII promotes spontaneous Ca2+ release events in a rodent model of early stage diabetes: The arrhythmogenic substrate [PDF]

open access: yes, 2016
Background: Heart failure and arrhythmias occur more frequently in patients with type 2 diabetes (T2DM) than in the general population. T2DM is preceded by a prediabetic condition marked by elevated reactive oxygen species (ROS) and subclinical ...
Anderson, Mark E.   +9 more
core   +3 more sources

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