Results 111 to 120 of about 3,537,545 (288)

Correcting the optimally selected resampling-based error rate: A smooth analytical alternative to nested cross-validation [PDF]

open access: yes, 2011
High-dimensional binary classification tasks, e.g. the classification of microarray samples into normal and cancer tissues, usually involve a tuning parameter adjusting the complexity of the applied method to the examined data set.
Augustin, Thomas   +2 more
core   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Predictability of Mandibular Autorotation After Maxillary Repositioning in Orthognathic Surgery: A Systematic Review with Exploratory Quantitative Synthesis

open access: yesApplied Sciences
This systematic review aimed to evaluate the available evidence on methods used to predict mandibular autorotation after maxillary repositioning in orthognathic surgery. A systematic search of PubMed/MEDLINE, Cochrane Library, Scopus, Google Scholar, and
Andrii Hresko   +3 more
doaj   +1 more source

Predicting Errors in Concurrent Systems

open access: yes, 2017
Die Verbreitung von Multikernprozessoren hat die parallele Programmierung allgegenwärtig gemacht. Parallele Programmierung ist schwierig, da sie die Entwicklung auf Grund vielfacher Kontrollflüsse und Nicht-Determinismus fehleranfällig macht. Zusätzlich gibt es neue Arten von Fehlern, wie z.B. Wettläufe, Verklemmungen oder Reihenfolgeverletzung.
openaire   +4 more sources

Choosing a Model and Strategy of Model Selection by Accumulated Prediction Error [PDF]

open access: yes
The purpose of the paper is to present and apply the accumulative one-step-ahead prediction error (APE) not only as a method (strategy) of model selection, but also as a tool of model selection strategy (meta-selection).
Mariola Pilatowska
core  

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

open access: yesMolecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi   +6 more
wiley   +1 more source

Predicting the Encoding Error of SIRENs

open access: yesCoRR
Implicit Neural Representations (INRs), which encode signals such as images, videos, and 3D shapes in the weights of neural networks, are becoming increasingly popular. Among their many applications is signal compression, for which there is great interest in achieving the highest possible fidelity to the original signal subject to constraints such as ...
Jeremy Vonderfecht, Feng Liu
openaire   +3 more sources

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

open access: yesMolecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee   +3 more
wiley   +1 more source

Prediction in measurement error models

open access: yesElectronic Journal of Statistics
We study the well known difficult problem of prediction in measurement error models. By targeting directly at the prediction interval instead of the point prediction, we construct a prediction interval by providing estimators of both the center and the length of the interval which achieves a pre-determined prediction level.
Jiang, Fei, Ma, Yanyuan
openaire   +2 more sources

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