Results 111 to 120 of about 3,708,416 (298)

Development, Insults and Predisposing Factors of the Brain’s Predictive Coding System to Chronic Perceptual Disorders—A Life-Course Examination

Brain Sciences
The predictive coding theory is currently widely accepted as the theoretical basis of perception and chronic perceptual disorders are explained as the maladaptive compensation of the brain to a prediction error. Although this gives us a general framework
Anusha Yasoda-Mohan, Sven Vanneste
doaj   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

To update or to separate: Neural signatures and consequences of latent cause inference in episodic memory

NeuroImage
Episodic memories are leveraged to predict upcoming input. Latent Cause Theory (Gershman et al., 2017) predicts that after moderate prediction errors, existing memories will be updated by integrating new information, while after large prediction errors ...
Marius Boeltzig, Sophie Siestrup, Inês Bramão, Ricarda I. Schubotz   +3 more
doaj   +1 more source

Prediction of discretization error using the error transport equation

Journal of Computational Physics, 2017
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Ismail B. Celik, Don Roscoe Parsons III
openaire   +4 more sources

Prediction error dependent changes in brain connectivity during associative learning [PDF]

, 2009
One of the fundaments of associative learning theories is that surprising events drive learning by signalling the need to update one’s beliefs. It has long been suggested that plasticity of connection strengths between neurons underlies the learning ...
den Ouden, H.E.M.
core  

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

Predictive coding in psychopathology: mechanistic model or metaphorical re-description?

Frontiers in Human Neuroscience
Predictive coding (PC) has become a central framework in contemporary cognitive neuroscience, proposing that the brain operates as a hierarchical inference system that continuously minimizes the mismatch between predicted and actual sensory input.
Albandri Sultan Alotaibi
doaj   +1 more source

Wait for it: Predicted Error vs. Prediction Error in Language Processing

, 2016
Poster presented at 2015 meeting of the Society for the Neurobiology of ...
Alday, Phillip M., Sassenhagen, Jona, Coussens, Scott, Bornkessel-schlesewsky, Ina   +3 more
openaire   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

Molecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee, Alessia Marin, Shivani Yalala, Harri M. Itkonen   +3 more
wiley   +1 more source