Results 61 to 70 of about 2,094,029 (295)

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Aggregated functional data model for Near-Infrared Spectroscopy calibration and prediction [PDF]

, 2013
Calibration and prediction for NIR spectroscopy data are performed based on a functional interpretation of the Beer-Lambert formula. Considering that, for each chemical sample, the resulting spectrum is a continuous curve obtained as the summation of ...
Dias, Ronaldo, Garcia, Nancy L., Ludwig, Guilherme, Saraiva, Marley A.   +3 more
core  

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Prediction Error Analysis of Finite-Control-Set Model Predictive Current Control for IPMSMs

Energies, 2018
Finite-control-set model predictive current control (FCS-MPCC) has been widely investigated in the field of motor control. When the discrete motor prediction model is not obtained accurately, prediction error often occurs, which can result in improper ...
Jian Li, Xiaoyan Huang, Feng Niu, Chaojie You, Lijian Wu, Youtong Fang   +5 more
doaj   +1 more source

Saccadic Predictive Vision Model with a Fovea

, 2018
We propose a model that emulates saccades, the rapid movements of the eye, called the Error Saccade Model, based on the prediction error of the Predictive Vision Model (PVM).
Hazoglou, Michael, Hylton, Todd
core   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Functional movement disorder is associated with abnormal interoceptive brain activity: a task-based functional MRI study

Frontiers in Psychiatry
BackgroundAberrant interoceptive processing has been hypothesized to contribute to the pathophysiology of functional neurological disorder, although findings have been inconsistent.
Primavera A. Spagnolo, Primavera A. Spagnolo, Primavera A. Spagnolo, Jacob A. Parker, Mark Hallett, Silvina G. Horovitz   +5 more
doaj   +1 more source

Magnetoencephalography Responses to Unpredictable and Predictable Rare Somatosensory Stimuli in Healthy Adult Humans

Frontiers in Human Neuroscience, 2021
Mismatch brain responses to unpredicted rare stimuli are suggested to be a neural indicator of prediction error, but this has rarely been studied in the somatosensory modality. Here, we investigated how the brain responds to unpredictable and predictable
Qianru Xu, Qianru Xu, Chaoxiong Ye, Chaoxiong Ye, Jarmo A. Hämäläinen, Elisa M. Ruohonen, Xueqiao Li, Piia Astikainen   +7 more
doaj   +1 more source

Closed-Loop Statistical Verification of Stochastic Nonlinear Systems Subject to Parametric Uncertainties

, 2017
This paper proposes a statistical verification framework using Gaussian processes (GPs) for simulation-based verification of stochastic nonlinear systems with parametric uncertainties.
ang, bishop, clarke, desautels, elliott, gotovos, kozarev, kulesza, maler, quindlen, rasmussen, tipping, topcu   +12 more
core   +1 more source

Performance Prediction of Nonbinary Forward Error Correction in Optical Transmission Experiments [PDF]

, 2016
In this paper, we compare different metrics to predict the error rate of optical systems based on nonbinary forward error correction (FEC). It is shown that the correct metric to predict the performance of coded modulation based on nonbinary FEC is the ...
Alvarado, Alex, Rios-Müller, Rafael, Schmalen, Laurent   +2 more
core   +4 more sources