Results 51 to 60 of about 23,967,054 (309)

Accurate structure prediction of biomolecular interactions with AlphaFold 3

open access: yesNature
The introduction of AlphaFold 21 has spurred a revolution in modelling the structure of proteins and their interactions, enabling a huge range of applications in protein modelling and design2, 3, 4, 5–6.
Josh Abramson   +47 more
semanticscholar   +1 more source

HDPM: An Effective Heart Disease Prediction Model for a Clinical Decision Support System

open access: yesIEEE Access, 2020
Heart disease, one of the major causes of mortality worldwide, can be mitigated by early heart disease diagnosis. A clinical decision support system (CDSS) can be used to diagnose the subjects’ heart disease status earlier.
Norma Latif Fitriyani   +3 more
semanticscholar   +1 more source

Stereotactic Body Radiation Therapy for Pediatric, Adolescent, and Young Adult Patients With Osteosarcoma: Local Control Outcomes With Dosimetric Analysis

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background/Objectives Osteosarcoma is a radioresistant tumor that may benefit from stereotactic body radiation therapy (SBRT) for locoregional control in metastatic/recurrent disease. We report institutional practice patterns, outcomes, toxicity, and failures in osteosarcoma patients treated with SBRT.
Jenna Kocsis   +13 more
wiley   +1 more source

Large-Eddy Simulation of Dry and Moist Atmospheric Boundary Layers and Analysis of the Model Convergence

open access: yesGaoyuan qixiang
By using the large eddy simulation (LES) version of the Weather Research and Forecasting (WRF) model, vertical structure and the feature of turbulent transportation of shallow-convective-cloud-topped atmospheric convective boundary layer was simulated in
Yixin ZHANG, Xindong PENG
doaj   +1 more source

PROBAST: A Tool to Assess Risk of Bias and Applicability of Prediction Model Studies: Explanation and Elaboration

open access: yesAnnals of Internal Medicine, 2019
Prediction models in health care aim to predict for an individual whether a particular outcome, such as disease, is present (diagnostic models) or whether it will occur in the future (prognostic models) (16).
K. Moons   +8 more
semanticscholar   +1 more source

Changes in Body Composition in Children and Young People Undergoing Treatment for Acute Lymphoblastic Leukemia: A Systematic Review and Meta‐Analysis

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Ongoing evidence indicates increased risk of sarcopenic obesity among children and young people (CYP) with acute lymphoblastic leukemia (ALL), often beginning early in treatment, persisting into survivorship. This review evaluates current literature on body composition in CYP with ALL during and after treatment.
Lina A. Zahed   +5 more
wiley   +1 more source

Minimum sample size for developing a multivariable prediction model: PART II ‐ binary and time‐to‐event outcomes

open access: yesStatistics in Medicine, 2018
When designing a study to develop a new prediction model with binary or time‐to‐event outcomes, researchers should ensure their sample size is adequate in terms of the number of participants (n) and outcome events (E) relative to the number of predictor ...
R. Riley   +6 more
semanticscholar   +1 more source

Parent‐to‐Child Information Disclosure in Pediatric Oncology

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Despite professional consensus regarding the importance of open communication with pediatric cancer patients about their disease, actual practice patterns of disclosure are understudied. Extant literature suggests a significant proportion of children are not told about their diagnosis/prognosis, which is purported to negatively ...
Rachel A. Kentor   +12 more
wiley   +1 more source

Characterization of extreme wave fields during Mediterranean tropical-like cyclones

open access: yesFrontiers in Marine Science
The Mediterranean Sea is a primary source of food, ecosystem services and economic activities and one of the most active cyclogenetic regions in the world, where the influence of orographic and morphological features of the relatively small basin plays ...
Silvio Davison   +6 more
doaj   +1 more source

DELWAVE 1.0: deep learning surrogate model of surface wave climate in the Adriatic Basin [PDF]

open access: yesGeoscientific Model Development
We propose a new point-prediction model, the DEep Learning WAVe Emulating model (DELWAVE), which successfully emulates the behaviour of a numerical surface ocean wave model (Simulating WAves Nearshore, SWAN) at a sparse set of locations, thus enabling ...
P. Mlakar   +8 more
doaj   +1 more source

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