ABSTRACT Objective To determine whether integration of serum neurofilament light chain (NfL) and cortical dysfunction improves diagnostic accuracy in amyotrophic lateral sclerosis (ALS) when applied alongside the Gold Coast criteria (GCC). Methods In this prospective study, 148 participants with suspected ALS were recruited (101 ALS and 47 with ALS ...
Aicee Dawn Calma +16 more
wiley +1 more source
The Empirical Bayes Variational Autoencoder-A Neural ODE Approach for Population Modeling in Pharmacology. [PDF]
Baaz M, Sjöberg A, Jirstrand M.
europepmc +1 more source
ABSTRACT Background Ischemic stroke, a major cause of mortality and long‐term disability, results from the abrupt cessation of cerebral blood flow due to vascular occlusion or rupture. Icosapent Ethyl (EPA‐EE), approved for hypertriglyceridemia, has anti‐inflammatory and antithrombotic properties that may lessen ischemic damage.
Mitra Mahmoudi Meymand +5 more
wiley +1 more source
Reagent-Free Prediction of Free-Ammonia Toxicity in Algal Systems Using Chlorophyll Fluorescence Transients and Interpretable Sparse Regression. [PDF]
Kishi M +4 more
europepmc +1 more source
Bi‐ and Mono‐Allelic RFC1 Expansion in a North American Cohort With Idiopathic Axonal Neuropathy
ABSTRACT Objective RFC1 biallelic repeat expansion is increasingly recognized as a cause of chronic idiopathic axonal polyneuropathy (CIAP), but it remains challenging to know who to test. This study aims to determine the prevalence of biallelic and monoallelic RFC1 expansions and their corresponding neuropathy phenotypes in CIAP patients and identify ...
Amro M. Stino +25 more
wiley +1 more source
Image analysis optimisation for carotenoid and anthocyanin content prediction in carrots: addressing colour parameter multicollinearity and genotypic diversity. [PDF]
Verme AC +3 more
europepmc +1 more source
Characterizing Cutaneous α‐Synuclein Deposition and Seeding Activity in Parkinson's Disease Subtypes
ABSTRACT Objective Cutaneous phosphorylated α‐synuclein (p‐syn) and α‐synuclein seeding activity are promising biomarkers for Parkinson's disease (PD), but their clinical value remains uncertain due to disease heterogeneity. This study evaluates these two biomarkers in PD patients to inform phenotype‐specific diagnosis and disease severity assessment ...
Yuting Jin +8 more
wiley +1 more source
Analyzing the geometric dependence of thermoelastic Q-factor in micro hemispherical resonators via a data-augmented CNN-transformer model. [PDF]
Yao Y, Yang G, Cheng R, Li W, Liu X.
europepmc +1 more source
Application of Machine Learning in Predicting the Properties of Two-Dimensional Semiconductor Materials. [PDF]
Yang J, Tang L, Wang Y, Wen J, Chen W.
europepmc +1 more source
Machine Learning-Based Support for Monitor Unit and Lung Shielding Estimation in Conventional Total Body Irradiation. [PDF]
Fiandra C +9 more
europepmc +1 more source

