Results 71 to 80 of about 827,518 (265)

The Accuracy of Dynamic Parameters for Prediction of Fluid Responsiveness in Elderly Patients with Septic Shock

International Journal of General Medicine
Sittikorn Paphawin,1,* Pongdhep Theerawit,2,* Detajin Junhasavasdikul,3 Yuda Sutherasan3 1Department of Medicine, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand; 2Division of Critical Care Medicine, Department of ...
Paphawin S, Theerawit P, Junhasavasdikul D, Sutherasan Y   +3 more
doaj  

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source

Research on hydraulic support column load prediction method based on extended multi-parameters

Gong-kuang zidonghua
In order to establish the mapping relationship between the hydraulic support column load and its dynamic response characteristics, and to realize dynamic prediction of the column load, a hydraulic support column load prediction method based on extended ...
WANG Yunfei, LI Ran, ZHAO Jiyun, CHEN Shiqi, XI Yunyi   +4 more
doaj   +1 more source

The development of methods for rapid prediction of frost resistance of ceramic products/Keraminių gaminių atsparumo šalčiui sparčiųjų prognozavimo metodų raida

Journal of Civil Engineering and Management, 1999
One of important parameters determining the quality of ceramic products is the resistance to frost. Frost resistance of ceramic brick can be determined exactly by direct unilateral freezing methods.
Asta Kičaitė
doaj   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source

On prediction accuracy of neutronics parameters of accelerator-driven system

EPJ Web of Conferences, 2017
Nuclear data-induced uncertainty of neutronics parameters of one specific ADS design is quantified. The nuclear data adjustment method with available integral data is employed to reduce the uncertainties, and usefulness of these integral data is ...
Chiba Go, Endo Tomohiro, Rooijen Wilfred van, Pyeon Cheol Ho   +3 more
doaj   +1 more source

On the Sample Information About Parameter and Prediction

Statistical Science, 2010
The Bayesian measure of sample information about the parameter, known as Lindley's measure, is widely used in various problems such as developing prior distributions, models for the likelihood functions and optimal designs. The predictive information is defined similarly and used for model selection and optimal designs, though to a lesser extent.
Ebrahimi, Nader, Soofi, Ehsan S., Soyer, Refik   +2 more
openaire   +4 more sources

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

Prediction of Hypertension Based on Anthropometric Parameters in Adolescents in Eastern Sudan: A Community-Based Study

Vascular Health and Risk Management
Awab H Saad,1 Ahmed A Hassan,2 Abdullah Al-Nafeesah,3 Ashwaq AlEed,3 Ishag Adam4 1Department of Medicine, Faculty of Medicine, Gadarif University, Gadarif, 32211, Sudan; 2Department of Medicine, Faculty of Medicine, University of Khartoum, Khartoum ...
Saad AH, Hassan AA, Al-Nafeesah A, AlEed A, Adam I   +4 more
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