Results 171 to 180 of about 167,767,624 (293)

Do Brain Extracellular Fluid Concentrations Predict PET‐Inferred Receptor Occupancy in Human CNS? A Mechanistic Model‐Based Analysis of Dopamine D2 Receptor Ligands

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
A mechanistic CNS PBPK model framework was applied to eight antipsychotic D2 receptor ligands, comparing brain extracellular fluid (brainECF) and brain cell membrane (brainM) as biophase for predicting human receptor occupancy compared against PET neuroimaging data. BrainM concentrations showed improved agreement with PET‐derived receptor occupancy for
Divakar Budda   +2 more
wiley   +1 more source

Kansas Drinking Water Annual Compliance Report

open access: yes, 2017
This report is a summary of Kansas water system's compliance with drinking water regulations for the calendar ...
Kansas Department of Health and Environment, Bureau of Water
core  

From Nature to Supply Chain: Exploring Biomimicry‐Based Pathways to Sustainability and Competitive Advantage

open access: yesCorporate Social Responsibility and Environmental Management, EarlyView.
ABSTRACT Inspired by insights gleaned from biomimicry theory, this paper addresses the persistent lack of theoretically grounded research in sustainable supply chain management (SSCM) and examines how nature‐inspired biomimicry principles could enhance various dimensions of its competitiveness. This study's theoretical contribution lies in its proposal
Susana Garrido   +4 more
wiley   +1 more source

1998 General Assembly Legislation Related to Water

open access: yes, 1998
The Virginia General Assembly held its regular session from January 14 to March 17, then reconvened April 22-23 to respond to the governor’s vetoes.
Manfre, Joseph   +1 more
core  

Real‐time lithology identification while drilling based on drill cuttings image analysis with ensemble learning

open access: yesDeep Underground Science and Engineering, EarlyView.
A lithology identification while drilling method was developed, integrating an automated cuttings sampling system, a smart drilling rig, and an ensemble learning model. Underground trials achieved 97.42% accuracy in real‐time identification of cuttings lithology and composition, enhancing hazard management and supporting unmanned drilling technology in
Kun Li   +7 more
wiley   +1 more source

Physics-guided networks for probabilistic hydrodynamic forecasting in canal systems. [PDF]

open access: yesEnviron Sci Ecotechnol
Liu W   +5 more
europepmc   +1 more source

Fracture evolution of a thick soft protection layer and the water inrush mechanism in overburden under longwall mining

open access: yesDeep Underground Science and Engineering, EarlyView.
Through shear–tensile creep tests and viscoelastic modeling, the fracture evolution of thick soft protective layers is clarified. Results show thickness‐dependent rheological failure modes that govern four types of roof water inrush, providing a mechanism‐based framework for hazard prediction and control. Abstract In the Jurassic coal‐bearing strata of
Mengnan Liu   +4 more
wiley   +1 more source

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