Results 131 to 140 of about 1,687,578 (280)

Regulation of Functions of the Brain and Body by the Principle of Predictive Coding: Implications for Impairments of the Brain-Gut Axis

open access: yesPsychological Topics, 2018
Lisa Feldman-Barrett, who has promoted a psychological constructivism theory of affect, recently proposed the Embodied Predictive Interoception Coding (EPIC) model of affect, based on the perspective of predictive coding.
Hideki Ohira
doaj   +2 more sources

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

open access: yesMolecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic   +10 more
wiley   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

open access: yesMolecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad   +2 more
wiley   +1 more source

Neurophysiological principles underlying predictive coding during dynamic perception-action integration

open access: yesNeuroImage
A major concept in cognitive neuroscience is that brains are “prediction machines”. Yet, conceptual frameworks on how perception and action become integrated still lack the concept of predictability and it is unclear how neural processes may implement ...
Roula Jamous   +5 more
doaj   +1 more source

Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy

open access: yesMolecular Oncology, EarlyView.
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen   +19 more
wiley   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

open access: yesMolecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault   +12 more
wiley   +1 more source

Intra Predictive Depth Map Coding Using Flexible Block Partitioning

open access: yes, 2015
Article number - 7160749A complete encoding solution for efficient intra-based depth map compression is proposed in this paper. The algorithm, denominated predictive depth coding (PDC), was specifically developed to efficiently represent the ...
Wegner, Krzysztof   +5 more
core   +1 more source

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

open access: yesMolecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim   +11 more
wiley   +1 more source

Predictive Coding with Temporal Invariance

open access: yes, 2012
Predictive coding and temporal invariance are two major unsupervised learning principles which have been used to explain the behavior of parts of the brain (most notably the striate cortex). Although both have been around for a number of years, no formal
Shaw, Jonathan M.
core  

Predictive Model for Carbon Content in Steel Grade Melting by Arc Furnace Based on Hybrid Coding Method

open access: yesTeshugang, 2010
A new genetic algorithm (GA) using hybrid coding method to train the neural network model for predication of carbon content in arc furnace steel is proposed, that is first to use binary coding method then to use decimal coding method continuously to ...
姜静, 孟利东, 李素玲, 姜琳
doaj  

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