Results 71 to 80 of about 9,049,447 (317)

Bayesian Predictive Coding

open access: yesCoRR
Predictive coding (PC) is an influential theory of information processing in the brain, providing a biologically plausible alternative to backpropagation. It is motivated in terms of Bayesian inference, as hidden states and parameters are optimised via gradient descent on variational free energy. However, implementations of PC rely on maximum \textit{a
Alexander Tschantz   +6 more
openaire   +2 more sources

Automated construction of cognitive maps with visual predictive coding

open access: yesbioRxiv
Humans construct internal cognitive maps of their environment directly from sensory inputs without access to a system of explicit coordinates or distance measurements.
James Gornet, Matthew Thomson
semanticscholar   +1 more source

Evolutionary computation with spatial receding horizon control to minimize network coding resources [PDF]

open access: yes, 2014
The minimization of network coding resources, such as coding nodes and links, is a challenging task, not only because it is a NP-hard problem, but also because the problem scale is huge; for example, networks in real world may have thousands or even ...
Mark S. Leeson   +3 more
core   +1 more source

Safety of Daprodustat for the Treatment of Chronic Kidney Disease Anemia: Final Analysis of a Multicenter Postmarketing Surveillance Study in Japan

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa   +7 more
wiley   +1 more source

Bidirectional predictive coding

open access: yesCoRR
Predictive coding (PC) is an influential computational model of visual learning and inference in the brain. Classical PC was proposed as a top-down generative model, where the brain actively predicts upcoming visual inputs, and inference minimises the prediction errors. Recent studies have also shown that PC can be formulated as a discriminative model,
Gaspard Oliviers   +2 more
openaire   +2 more sources

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Linear Predictive Coding for Speech Compression [PDF]

open access: yesMehran University Research Journal of Engineering and Technology, 2014
Telecommunication industry is growing and different services are rapidly introduced by different competitors to attract the users. Speech communication and its quality conservation is the most prevalent and common service provided by almost all companies.
Yasir Saleem, Faisal Hayat, Arslan Iqbal
doaj  

A new predictive coding model for a more comprehensive account of delusions

open access: yesLancet psychiatry
Attempts to understand the unshared reality of psychosis raise questions about how the brain models the world. Standard predictive coding approaches suggest that it does so by minimising mismatches between incoming sensory evidence and predictions.
Jessica N Harding   +5 more
semanticscholar   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

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