Results 81 to 90 of about 1,686,261 (278)
An interoceptive predictive coding model of conscious presence
Frontiers in Psychology, 2012 We describe a theoretical model of the neurocognitive mechanisms underlying conscious presence. The model is based on interoceptive prediction error and is informed by predictive models of agency, general models of hierarchical predictive coding and ...
Anil K. Seth +5 more
doaj +1 more source
FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
Predictive coding of multisensory timing [PDF]
Current Opinion in Behavioral Sciences, 2016 The sense of time is foundational for perception and action, yet it frequently departs significantly from physical time. In the paper we review recent progress on temporal contextual effects, multisensory temporal integration, temporal recalibration, and related computational models.
Shi, Zhuanghua, BURR, DAVID CHARLES
openaire +2 more sources
Predictive coding in neural circuits [PDF]
, 2023 The predictive coding theory provides a framework to explain various brain functions, including visual perception and expectation. Despite extensive research, the underlying circuit mechanisms of predictive coding are still poorly understood.
Huang, Shuzheng
core
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Evolutionary computation with spatial receding horizon control to minimize network coding resources [PDF]
, 2014 The minimization of network coding resources, such as coding nodes and links, is a challenging task, not only because it is a NP-hard problem, but also because the problem scale is huge; for example, networks in real world may have thousands or even ...
Mark S. Leeson +3 more
core +1 more source
Computational components of visual predictive coding circuitry
Frontiers in Neural CircuitsIf a full visual percept can be said to be a ‘hypothesis’, so too can a neural ‘prediction’ – although the latter addresses one particular component of image content (such as 3-dimensional organisation, the interplay between lighting and surface colour ...
Stewart Shipp
doaj +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source