Results 91 to 100 of about 2,315,567 (250)
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Assessment of the Effect of Predictive Maintenance on the System Reliability
VetorIn this work, we assess the effect of predictive maintenance on the reliability of repairable systems. In reparable systems, the reliability assessment considering corrective and preventive maintenance is well defined, but not considering predictive one.
Alexandre Santos Francisco +2 more
doaj +1 more source
International Journal of Prognostics and Health Management, 2016 A simulation-based real options analysis (ROA) approach is used to determine the optimum predictive maintenance opportunity for a wind turbine with a remaining useful life (RUL) prediction.
Xin Lei, Peter A. Sandborn
doaj +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Predictive Maintenance as an Enabler for Maintenance-integrated Production Planning
, 2018 Although high machine availability is crucial for efficient production, maintenance and production planning are often done separately in practice. Predictive Maintenance enables the prediction of remaining useful life of machine components and thus makes
Reinhart, Gunther, Zhai, Simon
core +1 more source
Cost-Effectiveness of Predictive Maintenance for Offshore Wind Farms: A Case Study
EnergiesThe successful implementation of predictive maintenance for offshore wind farms suffers from a poor understanding of the consequential short-term impacts and a lack of research on how to evaluate the cost-efficiency of such efforts.
Rasmus Dovnborg Frederiksen +4 more
doaj +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
On the Use of Time-Limited Information for Maintenance Decision Support: A Predictive Approach under Maintenance Constraints [PDF]
, 2013 11 pagesInternational audienceThis paper deals with a gradually deteriorating system operating under an uncertain environment whose state is only known on a finite rolling horizon. As such, the system is subject to constraints.
Grall, Antoine +3 more
core +1 more source
A literature review-based evaluation framework for maintenance strategy selection in heavy vehicles
Results in EngineeringEffective maintenance strategies are critical for ensuring operational reliability, minimizing downtime, and optimizing resource utilization in fleet-based industrial operations.
Malihe Goli +2 more
doaj +1 more source
Journal of Advanced Mechanical Sciences, 2023 This research review article explores the potential of integrating machine tool wear monitoring and ML algorithms for predictive maintenance. It synthesizes the latest research in the field, while discussing the benefits and challenges of various ...
S. Ganeshkumar
doaj