Results 91 to 100 of about 2,210,189 (286)

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source

Derivation of a cost model to aid management of CNC machine tool accuracy maintenance [PDF]

, 2015
Manufacturing industries strive to produce improved component accuracy while not reducing machine tool availability or production throughput. The accuracy of CNC production machines is one of the critical factors in determining the quality of these ...
Longstaff, Andrew P., Fletcher, Simon, Shagluf, Abubaker   +2 more
core   +3 more sources

Cost-Effectiveness of Predictive Maintenance for Offshore Wind Farms: A Case Study

Energies
The successful implementation of predictive maintenance for offshore wind farms suffers from a poor understanding of the consequential short-term impacts and a lack of research on how to evaluate the cost-efficiency of such efforts.
Rasmus Dovnborg Frederiksen, Grzegorz Bocewicz, Grzegorz Radzki, Zbigniew Banaszak, Peter Nielsen   +4 more
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Assessment of the Effect of Predictive Maintenance on the System Reliability

Vetor
In this work, we assess the effect of predictive maintenance on the reliability of repairable systems. In reparable systems, the reliability assessment considering corrective and preventive maintenance is well defined, but not considering predictive one.
Alexandre Santos Francisco, Marcos Vinícius Cardoso Lacerda, Luis Alberto Duncan Rangel   +2 more
doaj   +1 more source

International Journal of Prognostics and Health Management, ISSN 2153-2648, 2016 008 PHM-Based Wind Turbine Maintenance Optimization Using Real Options

International Journal of Prognostics and Health Management, 2016
A simulation-based real options analysis (ROA) approach is used to determine the optimum predictive maintenance opportunity for a wind turbine with a remaining useful life (RUL) prediction.
Xin Lei, Peter A. Sandborn
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Enhancing Predictive Maintenance Through Detection of Unrecorded Track Work

Predictive maintenance can help infrastructure managers to reduce costs and improve railway availability while ensuring safety. However, its accuracy depends on reliable data from various sources, especially track measurement data.
Florian Gerhold, Stefan Marschnig, Jan Schatzl, Markus Loidolt   +3 more
core   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

A comprehensive review on artificial intelligence driven predictive maintenance in vehicles: technologies, challenges and future research directions

Discover Applied Sciences
Predictive maintenance has rapidly grown in automotive industries with the advancements in artificial intelligence (AI) technologies like machine learning, deep learning, and now generative AI.
Yashashree Mahale, Shrikrishna Kolhar, Anjali S. More   +2 more
doaj   +1 more source