Results 71 to 80 of about 2,210,189 (286)

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Predictive Maintenance with Linguistic Text Mining

open access: yesMathematics
The escalating intricacy of industrial systems necessitates strategies for augmenting the reliability and efficiency of industrial machinery to curtail downtime. In such a context, predictive maintenance (PdM) has surfaced as a pivotal strategy.
Alberto Postiglione, Mario Monteleone
doaj   +1 more source

Prediction of software maintenance costs [PDF]

open access: yes, 2001
This thesis is concerned with predicting the costs of maintaining a computer program prior to the software being developed. The ubiquitous nature of software means that software maintenance is an important activity, and evidence exists to support the contention that it is the largest and most costly area of endeavour within the software domain.
openaire   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Forecasting models analysis for predictive maintenance

open access: yesFrontiers in Manufacturing Technology
IntroductionThis study explores the shift toward predictive maintenance through real-time data analytics to minimize machine downtime and improve machinery insights in industrial environments. Predictive maintenance aims to enable proactive interventions
Marco Belim   +3 more
doaj   +1 more source

ammar-n-abbas/Predictive-Maintenance-BC-IOHMM-DRL: v1.0.0

open access: yes
Hierarchical Framework for Interpretable Deep Reinforcement Learning Based- Predictive Maintenance (Applied to NASA Turbofan engine ...
Ammar N. Abbas
core   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

SUPREME SUstainable PREdictive Maintenance for manufacturing Equipment

open access: yes, 2022
6 S.Productivity improvements have major impact on economy and competitiveness in European manufacturing industry. Industrial maintenance contributes largely to this competitiveness through reliability and availability of production equipment. Especially
Boulet, Pierrick   +5 more
core   +1 more source

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