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Clinical prediction models [PDF]
_Dear Editor:_ The number of articles presenting a neurosurgical prediction model is rapidly increasing. Although the number of publications reporting a clinical prediction model in _Child’s Nervous System, Journal of Neurosurgery Pediatrics_, and _Pediatric Neurosurgery_ is relatively constant over the years (Fig.
Mijderwijk, HJ +3 more
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Prognostic research focuses on the prediction of the future course of a given disease in probability terms. Prognostication is performed by clinical decision makers by using risk prediction models that allow us to estimate the probability that a specific event occurs in a given patient over a predefined time period conditional on prognostic factors ...
Tripepi G +5 more
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Polyhexamethyleneguanidine phosphate (PHMG-P) is one of the causative agents of humidifier disinfectant-induced lung injury. Direct exposure of the lungs to PHMG-P causes interstitial pneumonia with fibrosis.
Jeongah Song +5 more
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The predictive brain model in diagnostic reasoning
Introduction: Clinical diagnosis is a pivotal and highly valued skill in medical practice. Most current interventions for teaching and improving diagnostic reasoning are based on the dual process model of cognition.
Tow Keang Lim
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3D Compartmentalised Human Pluripotent Stem Cell–derived Neuromuscular Co-cultures
Human neuromuscular diseases represent a diverse group of disorders with unmet clinical need, ranging from muscular dystrophies, such as Duchenne muscular dystrophy (DMD), to neurodegenerative disorders, such as amyotrophic lateral sclerosis (ALS).
Peter Harley +5 more
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Model-Free Predictive Control and Its Applications
Predictive control offers many advantages such as simple design and a systematic way to handle constraints. Model predictive control (MPC) belongs to predictive control, which uses a model of the system for predictions used in predictive control. A major
Muhammad Nauman +2 more
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Pregnane X receptor (PXR) is a key nuclear receptor that mediates drug metabolism and stimulates hepatocyte proliferation. However, the lack of PXR expression in human pluripotent stem cell-derived hepatocytes limits their application for drug screening ...
Hyemin Kim +5 more
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THE METHODOLOGY OF CONCEPTUAL MODELING IN ENVIRONMENTAL DESIGN AS A DESIGN AREA
The need to deepen the scientific base for the specialist area of Environmental Design with the use of the high potential of the general scientific categorical/systemic methodology has suggested developing a methodology for conceptual modeling in the ...
Tolstova Alexandra A.
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A worldwide survey on the use of animal‐derived materials and reagents in scientific experimentation
The use of cell and tissue‐based methods in basic, applied and regulatory science has been increasing exponentially. Animal‐derived components, including serum, coating materials, growth factors and antibodies are routinely used in cell/tissue cultures ...
Manuela Cassotta +7 more
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Clinical prediction models [PDF]
Clinical prediction models (also known as prognostic models, risk scores) are mathematical equations that relate multiple predictors (risk factors, co-variates) to the probability of having a disease or condition (diagnostic) or the probability that an event will happen in the future (prognostic).
Ranstam, J, Cook, J, Collins, G
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