Results 91 to 100 of about 1,068,736 (293)

Human Computation and Convergence

, 2015
Humans are the most effective integrators and producers of information, directly and through the use of information-processing inventions. As these inventions become increasingly sophisticated, the substantive role of humans in processing information ...
A Clark, AF Dugas, AJ Westphal, AW Woolley, B Resch, C Cardamone, CC Martin, D Blair, DW McDonald, E Desurvire, E Hansson, E Simperl, F Carrera, F Tang, G Tononi, GA Miller, H Rittel, H-Q Chong, I Garcia, J Ginsberg, JL Dickinson, JL Dickinson, KA Greene, KA Greene, L Ahn von, M Blumberg, M Brambilla, M Brasier, M Krause, MJ Endres, P Meier, P Michelucci, P Michelucci, P Michelucci, PE Smaldino, R Vigo, S Perathoner, SKM Yi, T Bücheler, T Shreejoy, TP Pavlic   +40 more
core   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Predictive Processing, Implicit and Explicit

, 2022
Preprint artykułu, który ukaże się w pracy zbiorowej: R. Thompson (ed). Routledge Handbook of Philosophy of Implicit Cognition. Routledge.
openaire   +5 more sources

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Learned Predictiveness Speeds Visual Processing

Psychological Science, 2012
When humans learn that the presence of a cue predicts the likelihood of an outcome, they can exploit this learned predictiveness, such that formation of subsequent associations between that cue and new outcomes is facilitated. Could such enhanced selection for association arise early enough to facilitate low-level visual processing?
O'Brien, Jennifer L., Raymond, Jane E.
openaire   +2 more sources

Updating Prediction Models for Predictive Process Monitoring

, 2022
Junta de Andalucía EKIPMENT-PLUS (P18-FR-2895)
Alfonso E. Márquez-Chamorro, Isabel A. Nepomuceno-Chamorro, Manuel Resinas, Antonio Ruiz-Cortés   +3 more
openaire   +3 more sources

Pain Asymbolia as Depersonalization for Pain Experience. An Interoceptive Active Inference Account

Frontiers in Psychology, 2020
“Mineness,” also called “subjective presence” or “personalization,” is the feeling that experiences belong to a continuing self. This article argues that mineness is produced by processes of interoceptive active inference that model the self as the ...
Philip Gerrans
doaj   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source