Results 131 to 140 of about 7,717,977 (381)

Impact of APOE ε4 Genotype Load on Cognitive Function and Lipid Metabolism in Patients With Cerebral Small Vessel Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Apolipoprotein ε4 (APOE ε4) is a potent genetic risk factor for Alzheimer's disease (AD). However, its role in cerebral small vessel disease (CSVD) remains unclear. Given the clinical and pathological similarities between CSVD and AD, this study aimed to investigate the associations of APOE ε4 gene dosage with cognitive function and
Tingru Jin, Haocheng Yang, Feng Liu, Sihao Lin, Junru Hu, Jian Wang, Yulan Gou   +6 more
wiley   +1 more source

New evidence on the validity of the selection methods for recruitment to general practice training: a cohort study

BJGP Open
Background: Selection into UK-based GP training has used the Multi-Specialty Recruitment Assessment (MSRA) and a face-to-face selection centre (SC). The MSRA comprises of a situational judgement test and clinical problem-solving test.
Paul A Tiffin, Emma Morley, Lewis W Paton, Fiona Patterson   +3 more
doaj   +1 more source

Responses to traumatic brain injury screening questions and suicide attempts among those seeking Veterans Health Administration mental health services

Frontiers in Psychiatry, 2016
Background: Psychometrically sound screening tools available to aid in the identification of lifetime history of traumatic brain injury (TBI) are limited.
Alexandra Lindsay Schneider, Trisha Ann Hostetter, Beeta Yazmeen Homaifar, Beeta Yazmeen Homaifar, Beeta Yazmeen Homaifar, Jeri Erica Forster, Jeri Erica Forster, Jeri Erica Forster, Bridget Bulman Matarazzo, Bridget Bulman Matarazzo, Jennifer H. Olson-Madden, Jennifer H. Olson-Madden, Jennifer H. Olson-Madden, Joe eHuggins, Lisa Anne Brenner, Lisa Anne Brenner, Lisa Anne Brenner, Lisa Anne Brenner   +17 more
doaj   +1 more source

Predicting and validating microRNA targets.

Genome biology, 2004
Given that microRNAs select their targets by nucleotide base-pairing, it follows that it should be possible to find microRNA targets computationally. There has been considerable progress, but assessing success and biological significance requires a move into the 'wet' lab.
openaire   +2 more sources

Validating Predictions from Climate Envelope Models

PLoS ONE, 2013
Climate envelope models are a potentially important conservation tool, but their ability to accurately forecast species' distributional shifts using independent survey data has not been fully evaluated. We created climate envelope models for 12 species of North American breeding birds previously shown to have experienced poleward range shifts. For each
James I Watling, David N Bucklin, Carolina Speroterra, Laura A Brandt, Frank J Mazzotti, Stephanie S Romañach   +5 more
openaire   +4 more sources

Lessons Learned: Quality Analysis of Optical Coherence Tomography in Neuromyelitis Optica

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Optical coherence tomography (OCT)‐derived retina measurements are markers for neuroaxonal visual pathway status. High‐quality OCT scans are essential for reliable measurements, but their acquisition is particularly challenging in eyes with severe visual impairment, as often observed in neuromyelitis optica spectrum disorders ...
Hadi Salih, Sara Samadzadeh, Charlotte Bereuter, Seyedamirhosein Motamedi, Claudia Chien, Pablo Villoslada, Hadas Stiebel‐Kalish, Nasrin Asgari, Yang Mao‐Draayer, Marius Ringelstein, Joachim Havla, Marco Aurélio Lana Peixoto, Ho Jin Kim, Jacqueline Palace, Maria Isabel Leite, Srilakshmi M. Sharma, Fereshteh Ashtari, Rahele Kafieh, Lekha Pandit, Orhan Aktas, Philipp Albrecht, Letizia Leocani, Itay Lotan, Sasitorn Siritho, Jérôme de Seze, Romain Marignier, Caroline Froment Tilikete, Denis Bernardi Bichuetti, Ivan Maynart Tavares, Ayse Altintas, Anu Jacob, Saif Huda, Ibis Soto de Castillo, Lawrence J. Cook, Michael R. Yeaman, Axel Petzold, Alexander U. Brandt, Friedemann Paul, Frederike C. Oertel, Hanna G. Zimmermann, with the Guthy Jackson Charitable Foundation—International Clinical Consortium and CROCTINO Collaborators   +40 more
wiley   +1 more source

From the lab to the field: envelopes, dictators and manners [PDF]

Results are reported of the first natural field experiment on the dictator game, where subjects are unaware that they participate in an experiment. In contrast to predictions of the standard economic model, dictators show a large degree of pro-social ...
Stoop, Jan
core   +1 more source

Investigating the predictive validity of an emergency department mental health triage tool [PDF]

, 2013
Natisha Sands, Stephen Elsom, Michael Berk, Jennifer Hosking, Roshani Prematunga, Marie Gerdtz   +5 more
openalex   +1 more source

Frailty Exacerbates Disability in Progressive Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background To evaluate frailty in severe progressive multiple sclerosis (PMS) and to investigate the underlying mechanisms. Methods This prospective, cross‐sectional, multicenter study enrolled a late severe PMS group requiring skilled nursing (n = 53) and an age, sex, and disease duration‐matched control PMS group (n = 53).
Taylor R. Wicks, Anna Wolska, Diala Ghazal, Dejan Jakimovski, Bianca Weinstock‐Guttman, Alexander Burnham, Niels Bergsland, Michael G. Dwyer, Alan T. Remaley, Robert Zivadinov, Murali Ramanathan   +10 more
wiley   +1 more source

Predictive validity of Matura for the psychology study [PDF]

Psihološka Obzorja, 2000
Introducing Matura as a secondary school final examination and as a selection instrument for University changed many things in the Slovenian education sister in the last few years.
Gašper Cankar
doaj