Results 161 to 170 of about 1,271,973 (317)

Predictive value of EASIX for CKD patients with CRS. [PDF]

Medicine (Baltimore)
Zhao D, Zhang F, Wang H, Tian H.
europepmc   +1 more source

Predictive Value of Troponin I, Creatinine Kinase Isoenzyme and the New Japanese Severity Score in Severe Acute Pancreatitis

Xiaoxing Wei,1,2,* Shengteng Guo,1,* Qinghua Wang1 1School of Nursing (School of Gerontology), Binzhou Medical University, Binzhou, Shandong, People’s Republic of China; 2Intensive Care Unit, Binzhou Medical University Hospital, Binzhou, Shandong,
Wang Q, Wei X, Guo S
core  

ESR1 methylation and ESR1 mutations in circulating tumor cells (CTCs) and paired plasma‐cfDNA of advanced breast cancer patients: A feasibility proof‐of‐concept study

Molecular Oncology, EarlyView.
Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou, Athina Markou, Eleonora Nicolo, Mara S Serafini, Qiang Zhang, Youbin Zhang, Lorenzo Gerratana, Andrew A. Davis, Huiping Liu, William J Gradishar, Carolina Reduzzi, Massimo Cristofanilli, Evi Lianidou   +12 more
wiley   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

Molecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi, Karolina Krzesińska, Ludovica Beltrame, Pablo Sánchez‐Izquierdo Besora, Matteo Tiberti, Mef Nilbert, Anna Rohlin, Elena Papaleo   +7 more
wiley   +1 more source

CHADS2 score has a better predictive value than CHA2DS2-VASc score in elderly patients with atrial fibrillation

, 2016
Yunli Xing, Qing Ma, Xiaoying Ma, Cuiying Wang, Dai Zhang, Ying Sun Department of Geriatrics and Gerontology, Beijing Friendship Hospital, Capital Medical University, Beijing, People’s Republic of China Aim: The study aims to compare the ability ...
Ma Q, Wang CY, Zhang D, Ma XY, Xing YL, Sun Y   +5 more
core  

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source

Evidence Based Medicine; Positive and negative predictive values of diagnostic tests

طب اورژانس ایران, 2015
Saeed Safari, Alireza Baratloo
doaj  

Comparison of the Predictive Value of Neutrophil Percentage-to-Albumin Ratio and Modified Glasgow Prognostic Score for the Risk of Stroke-Associated Pneumonia Among Stroke Patients

Zhu Tian,1 Yufeng Lin,1 Yang Song,1 Chi Zhang,2 Zhiyun Wang1 1Department of Neurology, Tianjin First Central Hospital, Tianjin, 300192, People’s Republic of China; 2Network and Information Office, Tianjin Medical University, Tianjin, 300070, People’s ...
Tian Z, Lin Y, Zhang C, Wang Z, Song Y
core  

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

Molecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen, Jiancheng Cheng, Ruili Hou, Xiaoyuan Zheng, Li Su, Maria Moksnes Bjaanæs, Anna Karlsson, Maria Planck, Johan Staaf, Åslaug Helland, Manel Esteller, David C. Christiani, Feng Chen, Xiaofei Cao, Ruyang Zhang   +14 more
wiley   +1 more source

Positive predictive value metrics for multicancer detection tests. [PDF]

J Med Screen
Pinsky PF, LeeVan EM, Patriotis C, Rubinstein WS.   +3 more
europepmc   +1 more source