Results 141 to 150 of about 1,271,973 (317)
Revista Portuguesa de Pneumologia, 2008 Introdução: A tuberculose extensivamente resistente (TBXDR) define -se como uma forma de tuberculose multirresistente (TBMR) com resistências adicionais às fluoroquinolonas e, pelo menos, a um dos antibacilares injectáveis seguintes: amicacina ...
Ana Sofia Vilariça +2 more
doaj
Molecular Oncology, EarlyView.EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
Predictive value of ADAMTS-13 on concealed chronic renal failure in COPD patients
, 2017 Mian Zeng, Qingui Chen, Wenjie Liang, Wanmei He, Haichong Zheng, Chunrong Huang Department of Medical Intensive Care Unit, the First Affiliated Hospital of Sun Yat-Sen University, Guangzhou, China Background: Impaired renal function is often neglected ...
Chen QG +5 more
core
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
Examining the predictive value of fertility preferences among Ghanaian women [PDF]
Despite extensive research, doubts remain regarding the degree of correspondence between prior stated fertility preferences and subsequent fertility behavior. Preference instability is a factor that potentially undermines predictiveness.
John Casterline +2 more
core
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Affective Value in the Predictive Mind
, 2017 Although affective value is fundamental in explanations of behavior, it is still a somewhat alien concept in cognitive science. It implies a normativity or directionality that mere information processing models cannot seem to provide. In this paper we trace how affective value can emerge from information processing in the brain, as described by ...
openaire +3 more sources
Hui Sun,1,* Haiying Liu,2,* Jinxia Li,1 Jinxin Kou,3 Can Yang1 1Clinical Laboratory, Xi’an International Medical Center Hospital, Xi’an, People’s Republic of China; 2Occupational Health Department, Xi’an Changan District Center for Disease ...
Liu H, Li J, Sun H, Yang C, Kou J
core
Measures of Predictive Success for Rating Functions [PDF]
Aim of our paper is to develop an adequate measure of predictive success and accuracy of rating functions. At first, we show that the common measures of rating accuracy, i.e. area under curve and accuracy ratio, respectively, lack of informative value of
Peter Reichling, Sebastian Ostrowski
core
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source