Results 121 to 130 of about 7,602,490 (304)
Structural and biochemical analysis of a B12 superbinder
FEBS Letters, EarlyView.BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
VALUE CREATION AND RESOURCE-BASED VIEW
, 2010 A PRESENTATION OF LINKAGES BETWEEN VALUE CREATION STUDIES AND RESOURCE-BASED ...
SCIARELLI, MAURO
core
FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
Analysis of the Clinical Predictive Value of the Novel Inflammatory Indices SII, SIRI, MHR and NHR in Patients with Acute Myocardial Infarction and Their Extent of Coronary Artery Disease [PDF]
Hui Sun,1,* Haiying Liu,2,* Jinxia Li,1 Jinxin Kou,3 Can Yang1 1Clinical Laboratory, Xi’an International Medical Center Hospital, Xi’an, People’s Republic of China; 2Occupational Health Department, Xi’an Changan District Center for Disease ...
Liu H, Li J, Sun H, Yang C, Kou J
core
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Predictive Value of Troponin I, Creatinine Kinase Isoenzyme and the New Japanese Severity Score in Severe Acute Pancreatitis [PDF]
Xiaoxing Wei,1,2,* Shengteng Guo,1,* Qinghua Wang1 1School of Nursing (School of Gerontology), Binzhou Medical University, Binzhou, Shandong, People’s Republic of China; 2Intensive Care Unit, Binzhou Medical University Hospital, Binzhou, Shandong,
Wang Q, Wei X, Guo S
core
The value of the negative predictive values [PDF]
BJOG: An International Journal of Obstetrics & Gynaecology, 1999 openaire +2 more sources
Predictive Factors of Suicide Attempt and Non-Suicidal Self-Harm in Emergency Department
Emergency, 2014 Introduction: Suicide is the third cause of mortality in America, second leading cause of death in developed countries, and one of the major health problems. Self-harm is self-inflicted damage to one’s self with or without suicidal intent. In the present
Saad Salman +5 more
doaj
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source