Results 101 to 110 of about 2,503,265 (261)

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Quantification of Metamorphopsia in Resolved Idiopathic Central Serous Chorioretinopathy: An Analysis Using M-CHARTS, Amsler Grid, and Optical Coherence Tomography

Clinical Ophthalmology
Barsha Suwal,1 Deepak Khadka,1 Arjun Shrestha,1 Rinkal Suwal,2 Bijay Khatri3 1Department of Ophthalmology, BP Eye Foundation, Hospital for Children, Eye, ENT, and Rehabilitation Services, Bhaktapur, Nepal; 2Department of Optometry, BP Eye Foundation ...
Suwal B, Khadka D, Shrestha A, Suwal R, Khatri B   +4 more
doaj  

Evaluation of a New Recombinant K39 Rapid Diagnostic Test for Sudanese Visceral Leishmaniasis. [PDF]

, 2006
A new rK39 rapid diagnostic dipstick test (DiaMed-IT-Leish) was compared with aspiration and a direct agglutination test (DAT) for diagnosis of visceral leishmaniasis (VL) in 201 parasitologically confirmed cases, 133 endemic controls, and in 356 ...
Davidson, R N, Kipngetich, S, Melaku, Y, Mueller, M, O'keeffe, C, Ritmeijer, K   +5 more
core   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Executive Stock Option Exercises and the Predictive Ability of Transaction Value [PDF]

, 2004
This paper investigates the predictive ability of executives’ stock option exercises by categorising all exercises by the overall value of the transaction. This measure incorporates the cost to the executive of exercising the option, together with the
Kyriacou, K, Mase, B
core  

Consciousness and the Wigner's friend problem

, 2006
It is generally agreed that decoherence theory is, if not a complete answer, at least a great step forward towards a solution of the quantum measurement problem.
A. Bassi, B. d’Espagnat, Bernard d’Espagnat, D. Bohm, H.P. Stapp, J.S. Bell, M. Schlick, R. Omnès   +7 more
core   +2 more sources

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

A Longitudinal Multimodal Imaging Study in Patients with Temporo-Insular Diffuse Low-Grade Tumors: How the Inferior Fronto-Occipital Fasciculus Provides Information on Cognitive Outcomes

Current Oncology
Background: Tractography allows the in vivo study of subcortical white matter, and it is a potential tool for providing predictive indices on post-operative outcomes.
Barbara Tomasino, Cinzia Baiano, Giuseppe Kenneth Ricciardi, Marta Maieron, Andrea Romano, Ilaria Guarracino, Miriam Isola, Maria De Martino, Serena D’Agostini, Daniele Bagatto, Teresa Somma, Miran Skrap, Tamara Ius   +12 more
doaj   +1 more source

UTICAJ BAZIČNO-MOTORIČKIH SPOSOBNOSTI NA REZULTATE SPOSOBNOSTI SPRINTERSKOG TRČANJA [PDF]

Sport Mont, 2009
The aim of this research was to determine the degree and characteristics of the link between sprinting sports results in the case of the 60 meter sprint and the basic-motor abi- lities of the elementary school students of the “Radojica Perović ...
Niko Raičković, Nataša Branković
doaj  

The Sign RCA Models: Comparing Predictive Accuracy of VaR Measures [PDF]

Evaluating Value at Risk (VaR) methods of predictive accuracy in an objective and effective framework is important for both efficient capital allocation and loss prediction.
Joanna Górka
core