Results 81 to 90 of about 1,271,973 (317)

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Predictive value of plasma parameters in the risk of postpartum ketosis in dairy cows

Journal of Veterinary Research, 2017
Introduction: The predictive value of selected parameters in the risk of ketosis and fatty liver in dairy cows was determined.
Cao Yu, Zhang Jiang, Yang Wei, Xia Cheng, Zhang Hong-You, Wang Yan-Hui, Xu Chuang   +6 more
doaj   +1 more source

Predictive Value of Osteoporosis Risk Factors for Bone Loss

, 2003
Osteoporosis is a serious and costly public health problem. It is important that subjects with risk for bone loss determine in a way that is economical and practical.
Merih Eryavuz Sarıdoğan, İlhan Karacan, Şafak S. Karamehmetoğlu, İmdat Özkul   +3 more
core  

Prognostic and predictive value of TP53 mutations in node-positive breast cancer patients treated with anthracycline- or anthracycline/taxane-based adjuvant therapy : results from the BIG 02-98 phase III trial [PDF]

, 2012
Introduction: Pre-clinical data suggest p53-dependent anthracycline-induced apoptosis and p53-independent taxane activity. However, dedicated clinical research has not defined a predictive role for TP53 gene mutations. The aim of the current study was to
Emmanuel Quinaux, Prudence A Francis, Lynnette Fernández-Cuesta, Dell'Orto, P, P. Falagan Lotsch, C. Oakman, A. D. Leo, Pierre Hainaut, Hainaut, P, Azambuja, Evandro De, P. A. Francis, Magali Olivier, D. Larsimont, Larsimont, D, E. Quinaux, G. Viale, Dolci, M Stella, M. S. Dolci, Martine Piccart-Gebhart, Francis, Prudence A, Oakman, C, Dell'orto, Patrizia, Viale, Giuseppe, Evandro De Azambuja, Priscila Falagan-Lotsch, Olivier, Magali, Crown, John, L. Fernández Cuesta, Ke-seay Smoth, Hainaut, Pierre, John Crown, Fernández-Cuesta, L, Viale, G, Leo, Angelo, Larsimont, Denis, M. Piccart Gebhart, Fernández-Cuesta, Lynnette, de Azambuja, Evandro, Giuseppe Viale, Falagan-Lotsch, P, Crown, J, Patrizia Dell'Orto, Piccart-Gebhart, Martine, M Stella Dolci, Piccart-Gebhart, M, Buyse, Marc, Quinaux, E, Denis Larsimont, M. Olivier, M. Buyse, Catherine Oakman, Quinaux, Emmanuel, P. Dell'orto, Olivier, M, Oakman, Catherine, Dolci, MS, Leo, Angelo Di, Buyse, M, Smoth, Ke-Seay, P. Hainaut, Smoth, KS, Azambuja, ED, Angelo Di Leo, J. Crown, Leo, AD, Dolci, Stella, E. D. Azambuja, Francis, P, Francis, PA, Falagan-Lotsch, Priscila, Marc Buyse, K. Smoth   +71 more
core   +1 more source

Positive predictive value and negative predictive value for pairs of alarm indicators.

, 2022
Positive predictive value and negative predictive value for pairs of alarm indicators.
Harriet Roggeveen (10431163), Estivern Evens (12915204), Rodnie Senat Delva (12915213), Melissa McRae (12915222), Omar Contigiani (12915201), Colette Badjo (12915216), Barbara Pawulska (12915219), Annick Lenglet (631247), Joost Hopman (370796), Carl-Frédéric Casimir (12915210), Cono Ariti (552950), Kate Clezy (3510953), Kessianne Charles (12915207), Heiman Wertheim (129740)   +13 more
core   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

The predictive value of arterial stiffness on major adverse cardiovascular events in individuals with mildly impaired renal function

, 2016
Jie Han,* Xiaona Wang,* Ping Ye, Ruihua Cao, Xu Yang, Wenkai Xiao, Yun Zhang, Yongyi Bai, Hongmei Wu Department of Geriatric Cardiology, Chinese PLA General Hospital, Beijing, People’s Republic of China *These authors contributed equally to  ...
Yang X, Ye P, Zhang Y, Xiao W, Han J, Wang X, Bai Y, Cao R, Wu H   +8 more
core  

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

FEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Quantification of Metamorphopsia in Resolved Idiopathic Central Serous Chorioretinopathy: An Analysis Using M-CHARTS, Amsler Grid, and Optical Coherence Tomography

Clinical Ophthalmology
Barsha Suwal,1 Deepak Khadka,1 Arjun Shrestha,1 Rinkal Suwal,2 Bijay Khatri3 1Department of Ophthalmology, BP Eye Foundation, Hospital for Children, Eye, ENT, and Rehabilitation Services, Bhaktapur, Nepal; 2Department of Optometry, BP Eye Foundation ...
Suwal B, Khadka D, Shrestha A, Suwal R, Khatri B   +4 more
doaj