Results 41 to 50 of about 77,842 (247)

Relationship of troponins with in-hospital mortality in adults with covid-19 in a colombian caribbean city: a nested case-control study

Microbes, Infection and Chemotherapy, 2023
Background: myocardial injury, characterized by elevated cardiac troponin levels, is a common finding in severe COVID-19 cases, occurring in up to 38% of patients. It has been identified as an independent predictor of mortality. Objective: our aim is to
MARIA CLARA OSPINO GUERRA, Carlos H. Murgas-Cañas, Jessica L. Ospino-Guzman, Lourdes Varela-Prieto, Rodolfo Cano-Rivera, Rusvelt Vargas-Moranth   +5 more
doaj   +1 more source

The Saccharomyces cerevisiae amino acid transporter Lyp1 has a broad substrate spectrum

FEBS Letters, EarlyView.
In Saccharomyces cerevisiae, Yeast Amino acid Transporter family members mediate the import of amino acids, ranging from substrate specialists to generalists. Here, we show that the specialist transporter, Lyp1, has a broader substrate spectrum than previously described, with affinity constants spanning from micromolar to millimolar.
Foteini Karapanagioti, Sebastian Obermaier, Dirk J. Slotboom, Bert Poolman   +3 more
wiley   +1 more source

HMGA1 Has Predictive Value in Response to Chemotherapy in Gastric Cancer

Current Oncology, 2021
Gastric cancer is a serious health problem worldwide. Although its incidence is decreasing, the five-year survival rate remains low. Thus, it is essential to identify new biomarkers that could promote better diagnosis and treatment of patients with ...
Diana Pádua, Débora Filipa Pinto, Paula Figueira, Carlos Filipe Pereira, Raquel Almeida, Patrícia Mesquita   +5 more
doaj   +1 more source

Unlocking the potential of tumor‐derived DNA in urine for cancer detection: methodological challenges and opportunities

Molecular Oncology, EarlyView.
Urine is a rich source of biomarkers for cancer detection. Tumor‐derived material is released into the bloodstream and transported to the urine. Urine can easily be collected from individuals, allowing non‐invasive cancer detection. This review discusses the rationale behind urine‐based cancer detection and its potential for cancer diagnostics ...
Birgit M. M. Wever, Renske D. M. Steenbergen   +1 more
wiley   +1 more source

Predictive value of the systemic immune inflammation (SII) index for stroke‐associated pneumonia

Brain and Behavior, 2023
Objective To investigate the predictive value of the systemic immune inflammation (SII) index on the occurrence of stroke‐associated pneumonia (SAP) in patients with acute stroke.
Zhanhang Cui, Sai Kuang, Xiaorong Yang, Ying Wang, Shanshan Gu, Hongyu Li, Huibin Chen, Yanbing Han, Haimei Sun   +8 more
doaj   +1 more source

Use of Interval Therapy with Benzodiazepines to Prevent Seizure Recurrence in Stressful Situations

Brain Sciences, 2022
Introduction: Antiseizure medications (ASMs) control 70–75% of seizures. Accepting stress as a trigger for seizures, intervention, at the time of predictable stress, should offer a therapeutic option.
Roy G. Beran
doaj   +1 more source

Subpar reporting of pre‐analytical variables in RNA‐focused blood plasma studies

Molecular Oncology, EarlyView.
Pre‐analytical variables strongly influence the analysis of extracellular RNA (cell‐free RNA; exRNA) derived from blood plasma. Their reporting is essential to allow interpretation and replication of results. By evaluating 200 exRNA studies, we pinpoint a lack of reporting pre‐analytical variables associated with blood collection, plasma preparation ...
Céleste Van Der Schueren, Philippe Decruyenaere, Francisco Avila Cobos, Johanna Bult, Jill Deleu, Laudonia Lidia Dipalo, Hetty Hilde Helsmoortel, Eva Hulstaert, Annelien Morlion, Elena Ramos Varas, Kathleen Schoofs, Wim Trypsteen, Eveline Vanden Eynde, Hanne Van Droogenbroeck, Kimberly Verniers, Jo Vandesompele, Anneleen Decock   +16 more
wiley   +1 more source

A comparative analysis of the different HIV testing techniques used in Zambia: data from a clinical performance study

BMC Research Notes
Background Approximately 40 million people globally are living with HIV (PLWH) and more than 50% of these PLWH reside in Eastern and Southern Africa. Zambia has an adult HIV-1 prevalence (ages 15–49) of 11.1 [10.5–11.6] %, among the highest in the world (
Loveness Mukuka, Andros Theo, Precious Simushi, Mowa Zambwe, Peter J. Chipimo   +4 more
doaj   +1 more source

Identification of functional and diverse circulating cancer‐associated fibroblasts in metastatic castration‐naïve prostate cancer patients

Molecular Oncology, EarlyView.
Cancer‐associated fibroblasts (CAFs) promote cancer growth, invasion (metastasis), and drug resistance. Here, we identified functional and diverse circulating CAFs (cCAFs) in patients with metastatic prostate cancer (mPCa). cCAFs were found in higher numbers and were functional and diverse in mPCa patients versus healthy individuals, suggesting their ...
Richell Booijink, Leon W. M. M. Terstappen, Eshwari Dathathri, Khrystany Isebia, Jaco Kraan, John Martens, Ruchi Bansal   +6 more
wiley   +1 more source

Diagnostic efficacy and importance of fine-needle aspiration cytology of thyroid nodules

Journal of Cytology, 2014
Background: Fine-needle aspiration cytology (FNAC) in the diagnosis of thyroid nodules is an easy and cost-effective method. The increase in malignancy rates of the excised nodules due to the high sensitivity and specificity rates of the FNAC is ...
Asli Muratli, Nilsen Erdogan, Sezgin Sevim, Isik Unal, Serap Akyuz   +4 more
doaj   +1 more source