Predicting Disease Progress with Imprecise Lab Test Results [PDF]
In existing deep learning methods, almost all loss functions assume that sample data values used to be predicted are the only correct ones. This assumption does not hold for laboratory test data. Test results are often within tolerable or imprecision ranges, with all values in the ranges acceptable.
arxiv
Glycosylated haemoglobin (HbA1c) and cortisol levels on admission to intensive care as predictors of outcome [PDF]
Objective: To evaluate the predictive value of glycosylated haemoglobin and cortisol on admission, in critical care patients. Design: Prospective, observational, single centre study. Setting: 14 bedded Intensive care unit of a tertiary-level university
Abela, Carmel J.+5 more
core
The power of microRNA regulation—insights into immunity and metabolism
MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto+2 more
wiley +1 more source
The lacey assessment of preterm infants: Predictive validity in early infancy
Background and Aim: The Lacey Assessment of Preterm Infants (LAPI) is reported to have low sensitivity but high specificity to predict neurological function.
Thanooja Naushad, Meena Natarajan
doaj +1 more source
Zipper: Addressing degeneracy in algorithm-agnostic inference [PDF]
The widespread use of black box prediction methods has sparked an increasing interest in algorithm/model-agnostic approaches for quantifying goodness-of-fit, with direct ties to specification testing, model selection and variable importance assessment.
arxiv
Predictive models of syncope causes in an outpatient clinic [PDF]
The investigation of unexplained syncope remains a challenging clinical problem. In the present study we sought to evaluate the diagnostic value of a standardized work-up focusing on non invasive tests in patients with unexplained syncope referred to a ...
Fromer, M.+7 more
core +1 more source
Identification of novel small molecule inhibitors of ETS transcription factors
ETS transcription factors play an essential role in tumourigenesis and are indispensable for sprouting angiogenesis, a hallmark of cancer, which fuels tumour expansion and dissemination. Thus, targeting ETS transcription factor function could represent an effective, multifaceted strategy to block tumour growth. The evolutionarily conserved E‐Twenty‐Six
Shaima Abdalla+9 more
wiley +1 more source
Charlson Comorbidity Index and other predictors of in-hospital mortality among adults with community-acquired pneumonia [PDF]
Objective: To compare the performance of Charlson Comorbidity Index (CCI) with those of the mental Confusion, Urea, Respiratory rate, Blood pressure, and age = 65 years (CURB-65) score and the Pneumonia Severity Index (PSI) as predictors of all-cause in ...
Laura Fuchs Bahlis+2 more
doaj +4 more sources
Background and Aims: A recent study suggested middle finger length-based formula as a better predictive guide compared with age-based formula for selecting uncuffed endotracheal tubes (ETTs) in children.
Priyam Saikia, Rohan S Thottan
doaj +1 more source
Bayesian Updating and Sequential Testing: Overcoming Inferential Limitations of Screening Tests [PDF]
Bayes' Theorem confers inherent limitations on the accuracy of screening tests as a function of disease prevalence. We have shown in previous work that a testing system can tolerate significant drops in prevalence, up until a certain well-defined point known as the $prevalence$ $threshold$, below which the reliability of a positive screening test drops
arxiv