Results 1 to 10 of about 278,879 (377)

The effects of conventional drugs in the treatment of rheumatoid arthritis on the serum lipids

Journal of Research in Medical Sciences, 2018
Background: Rheumatoid arthritis (RA) is a common chronic autoimmune disorder that leads to damage of human joints. There are various treatment approaches in which different drugs are prescribed which have several alterations in serum lipids.
Mansoor Karimifar, Mohammad S Sepehrifar, Hamidreza Moussavi, Mohammad B Sepehrifar, Peyman Mottaghi, Mansour Siavash, Mozhgan Karimifar   +6 more
doaj   +1 more source

Pharmacokinetics of Oral Prednisone at Various Doses in Dogs: Preliminary Findings Using a Naïve Pooled-Data Approach

Frontiers in Veterinary Science, 2020
This pilot study aimed to determine the plasma pharmacokinetics of prednisone and its active metabolite prednisolone following oral prednisone administration in dogs—using dosing regimens that cover anti-inflammatory to immuno-suppressive biological ...
Lionel Sebbag, Lionel Sebbag, Jonathan P. Mochel   +2 more
doaj   +1 more source

Successful management of colonic pythiosis in two dogs in Thailand using antifungal therapy

Veterinary Medicine and Science, 2022
Gastrointestinal pythiosis is a severe, progressive and often a fatal disease, which is caused by the aquatic pathogen Pythium insidiosum. Treatment is challenging due to the disease's resistance to antifungal drugs.
Pornphan Sukanan, Bongkot Suparp, Supattra Yongsiri, Piyarat Chansiripornchai, Sawang Kesdangsakonwut   +4 more
doaj   +1 more source

The effect of therapeutic glucocorticoids on the adrenal response in a randomized controlled trial in patients with rheumatoid arthritis [PDF]

, 2005
Objective. To measure the effect of low-dose systemic glucocorticoid treatment on the adrenal response to adrenocorticotropic hormone (ACTH) in patients with rheumatoid arthritis (RA). Methods.
Arnett, Buttgereit, Byyny, Chamberlain, Chikenza, Clark, Crofford, Edsbacker, Edsbacker, Greig, Gudbjornsson, Harbuz, Harbuz, Hench, Henzen, Hicklin, Hsu, Jasani, Kanik, Kirwan, Kirwan, Neeck, Rutgeerts, Schlaghecke, Shuster, Spiegel, Treadwell, Wood   +27 more
core   +1 more source

Microemulsions as Lipid Nanosystems Loaded into Thermoresponsive In Situ Microgels for Local Ocular Delivery of Prednisolone

Pharmaceutics, 2022
This study aimed to develop and evaluate thermoresponsive in situ microgels for the local ocular delivery of prednisolone (PRD) (PRD microgels) to improve drug bioavailability and prolong ocular drug residence time.
Rania Hamed, Amani D. Abu Kwiak, Yasmeen Al-Adhami, Alaa M. Hammad, Rana Obaidat, Osama H. Abusara, Rana Abu Huwaij   +6 more
doaj   +1 more source

Clinical presentation, diagnostic findings and outcome of dogs with presumptive spinal-only meningoencephalomyelitis of unknown origin [PDF]

, 2017
Objectives: To summarise clinical presentation, diagnostic findings and long-term outcome for dogs clinically diagnosed with meningoencephalomyelitis of unknown origin affecting the spinal cord alone.
Cardy, Coates, Csebi, Da Costa, De Risio, Dewey, Eminaga, Fenn, Granger, Griffin, Meric, Parry, Scott, Tipold   +13 more
core   +2 more sources

Optimizing the Use of Current Treatments and Emerging Therapeutic Approaches to Achieve Therapeutic Success in Patients with Inflammatory Bowel Disease

Gut and Liver, 2020
The current goal of inflammatory bowel disease (IBD) treatment is a symptom-free everyday life accompanied by mucosal healing with minimal use of corticosteroids.
Hiroshi Nakase
doaj   +1 more source

Brain vitamin D3-auto/paracrine system in relation to structural, neurophysiological, and behavioral disturbances associated with glucocorticoid-induced neurotoxicity

Frontiers in Cellular Neuroscience, 2023
IntroductionVitamin D3 (VD3) is a potent para/autocrine regulator and neurosteroid that can strongly influence nerve cell function and counteract the negative effects of glucocorticoid (GC) therapy.
Olha Lisakovska, Dmytro Labudzynskyi, Anna Khomenko, Dmytro Isaev, Alina Savotchenko, Ludmila Kasatkina, Serhii Savosko, Mykola Veliky, Ihor Shymanskyi   +8 more
doaj   +1 more source

Failure to achieve lupus low disease activity state (LLDAS) six months after diagnosis is associated with early damage accrual in Caucasian patients with systemic lupus erythematosus [PDF]

, 2017
Background: The aim was to assess the attainability and outcome of the lupus low disease activity state (LLDAS) in the early stages of systemic lupus erythematosus (SLE).
CAPPELLAZZO, GIULIA, Cauli, Alberto, Chessa, Elisabetta, Congia, Mattia, Floris, Alberto, Mathieu, Alessandro, Piga, Matteo   +6 more
core   +1 more source

Brain and Lung Abscesses in a 48-year-old Man with Focal and Segmental Glomerulosclerosis [PDF]

Journal of Clinical and Diagnostic Research, 2015
Focal segmental sclerosis (FSGS) is a common cause of idiopathic nephrotic syndrome in the adult population. A patient aged 48- year-old was admitted for evaluation of azotemia. Renal biopsy showed tip lesion FSGS and acute tubular necrosis.
Ali Momeni, Fereidoon Rahmani, Hamid Nasri   +2 more
doaj   +1 more source