Results 91 to 100 of about 278,879 (377)

Decoding the Pathophysiology of Autoimmune Diseases—Mechanism, Triggers, and Nanotherapeutics: A Review

Advanced NanoBiomed Research, EarlyView.
This review highlights how autoimmune diseases arise from intertwined immunological, genetic, and environmental factors, emphasizing gut microbiota dysbiosis as a pivotal driver. It outlines emerging nanotechnology‐based strategies—such as liposomes, hydrogels, and polymeric nanoparticles—that enhance targeted drug delivery, minimize systemic toxicity,
Md. Meraj Ansari, Yunhui Min, Eun‐Ju Ko, Doyoung Kwon, Rehan Khan, Young‐Ok Son   +5 more
wiley   +1 more source

Prednisolone adsorption on lung surfactant models: insights on the formation of nanoaggregates, monolayer collapse and prednisolone spreading

, 2017
The adsorption of prednisolone on a lung surfactant model was successfully performed using coarse grained molecular dynamics. The prednisolone coarse grained model was parameterized using a well-established cholesterol model and validated by using ...
Evelina D. Estrada-López, Erika Murce, M. P. P. França, A. S. Pimentel   +3 more
semanticscholar   +1 more source

Prednisolone is associated with a worse lipid profile than hydrocortisone in patients with adrenal insufficiency

Endocrine Connections, 2016
Objective Prednisolone is used as glucocorticoid replacement therapy for adrenal insufficiency (AI). Recent data indicate that its use in AI is associated with low bone mineral density.
M. Quinkler, B. Ekman, C. Marelli, S. Uddin, P. Zelissen, R. Murray   +5 more
semanticscholar   +1 more source

Case‐Based Immunology: B Cells and Systemic Sclerosis Interstitial Lung Disease

Arthritis &Rheumatology, EarlyView.
Interstitial lung disease (ILD) is an important complication of systemic sclerosis (SSc), with high mortality and morbidity. Recent clinical studies in SSc‐ILD have led to US Food and Drug Administration–approved therapies in SSc‐ILD. Importantly, evidence from these studies has been extrapolated to guide management of ILDs of other systemic autoimmune
Nina Goldman, Voon Ong, Christopher P. Denton   +2 more
wiley   +1 more source

Homologous ELISA for detection of prednisolone in human serum

Food and Agricultural Immunology, 2018
An enzyme-linked immunosorbent assay to measure prednisolone have been developed. An antibody was raised in rabbits using prednisolone-21-hemisuccinate (PSL-21-HS) conjugated to bovine serum albumin.
Dinesh Kumar, Harpal Singh, T. G. Shrivastav   +2 more
doaj   +1 more source

Vitamin D3 Modulates Impaired Crosstalk Between RANK and Glucocorticoid Receptor Signaling in Bone Marrow Cells After Chronic Prednisolone Administration

Frontiers in Endocrinology, 2018
The effectiveness of vitamin D3 (cholecalciferol) in counteracting the side effects of glucocorticoid (GC) therapy has been demonstrated previously. Abnormalities in systemic hormonal and local (cytokine) regulation of bone marrow (BM) cells may underlie
Ihor Shymanskyi, Olha Lisakovska, Anna Mazanova, Dmytro Labudzynskyi, Mykola Veliky   +4 more
doaj   +1 more source

Bronchial thermoplasty for severe asthma: A position statement of the Indian chest society

Lung India, 2020
Bronchial thermoplasty (BT) is an interventional bronchoscopic treatment for severe asthma. There is a need to define patient selection criteria to guide clinicians in offering the appropriate treatment options to patients with severe asthma. Methodology:
Karan Madan, Saurabh Mittal, Tejas M Suri, Avinash Jain, Anant Mohan, Vijay Hadda, Pavan Tiwari, Randeep Guleria, Deepak Talwar, Sudhir Chaudhri, Virendra Singh, Rajesh Swarnakar, Sachidanand J Bharti, Rakesh Garg, Nishkarsh Gupta, Vinod Kumar, Ritesh Agarwal, Ashutosh N Aggarwal, Irfan I Ayub, Prashant N Chhajed, Amit Dhamija, Raja Dhar, Sahajal Dhooria, Hari K Gonuguntla, Rajiv Goyal, Parvaiz A Koul, Raj Kumar, Nagarjuna Maturu, Ravindra M Mehta, Ujjwal Parakh, Vallandaramam Pattabhiraman, Narasimhan Raghupathi, Inderpaul Singh Sehgal, Arjun Srinivasan, Kavitha Venkatnarayan   +34 more
doaj   +1 more source

MRI and clinical resolution of a suspected intracranial toxoplasma granuloma with medical treatment in a domestic short hair cat [PDF]

, 2017
A two-year-old cat was presented with a left paradoxical vestibular syndrome. MRI of the brain revealed an extra-axial homogenously contrast enhancing mass in the region of the left caudal cerebellar peduncle.
Beltran, E, Crawford, A H, Drees, R
core   +1 more source

Cytokine pathways driving diverse tissue pathologies in rheumatoid arthritis

Arthritis &Rheumatology, Accepted Article.
Rheumatoid arthritis is a complex systemic disorder characterised primarily by articular inflammation and destruction with associated functional loss and reduced quality of life. RA is also associated with extra‐articular disease e.g. of the lung with potentially devastating clinical consequences.
Aurelie Najm, Lyn D. Ferguson, Iain B. McInnes   +2 more
wiley   +1 more source

Comparison of Prednisolone, Etoricoxib, and Indomethacin in Treatment of Acute Gouty Arthritis: An Open-Label, Randomized, Controlled Trial

Medical Science Monitor, 2016
Background At present there are several kinds of medicine for treating acute gout arthritis (AGA). This study compared the efficacy and safety of prednisolone, etoricoxib, and indomethacin in the treatment of AGA. Material/Methods This was an open-label,
Lingling Xu, Shi-qun Liu, Meiping Guan, Yao-ming Xue   +3 more
semanticscholar   +1 more source