Results 121 to 130 of about 205,860 (279)

Non‐invasive and efficient diabetic retinal mitochondrial repair nanoplatform based on engineered endothelial mitochondrial‐derived vesicles with dynamic integrated stress response modulation

open access: yesInterdisciplinary Medicine, EarlyView.
Under hyperglycemic conditions, mitochondrial dysfunction in retinal endothelial cells triggers excessive reactive oxygen species/reactive nitrogen species production, barrier protein degradation, and endothelial barrier breakdown in diabetic retinopathy.
Siyu Gui   +12 more
wiley   +1 more source

Recent progress on stimuli‐responsive chitosan‐based biomaterials as drug carriers

open access: yesInterdisciplinary Medicine, EarlyView.
This review discusses the recent progress in chitosan‐based drug delivery systems that respond to pH, redox, enzymes, reactive oxygen species, and combined stimuli. It examines design strategies, key mechanisms, and therapeutic applications, and also addresses current challenges while suggesting future approaches to enhance clinical translation and ...
Changlu Xu   +4 more
wiley   +1 more source

Multicenter experience using tofacitinib for treatment of refractory pediatric inflammatory bowel diseases in the United States

open access: yesJournal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives Tofacitinib is a selective Janus kinase (JAK‐1) inhibitor approved for the treatment of ulcerative colitis (UC) in adults. Data is limited in the pediatric population. The aim of this study was to evaluate the efficacy of tofacitinib in pediatric inflammatory bowel disease (IBD).
Denise D. Young   +10 more
wiley   +1 more source

Cariesprofilactic and parodontoprotective effects of oral gel “Quertulin” on rats, which received prednisolone

open access: yesJournal of Education, Health and Sport, 2017
Aim: To determine stomatoprotective effects of new complex phytogel “Quertulin” (quercetin + inulin + calcium citrate) on rats, which received prednisolone.
A. V. Valda, A. P. Levitsky
doaj  

Concurrent Manifestations of Type 1 Diabetes Mellitus and Nephrotic Syndrome in a Child with Unilateral Renal Hypo-dysplasia: A Case Report with Review of Literature

open access: yesIndian Pediatrics Case Reports
Background: Simultaneous occurrence of steroid-sensitive nephrotic syndrome (NS) and Type 1 diabetes mellitus (DM) in children is rare. Clinical description: A 21-month-old boy presented with generalized swelling with hypertension, with no significant ...
Shagufa Marakkar   +3 more
doaj   +1 more source

Alcoholic liver disease: State-of-the-art

open access: yesТерапевтический архив, 2014
The literature review gives the present views of the diagnosis and treatment of alcoholic liver disease (ALD) and data on the genetic markers associated with the development of ALD and alcohol addiction.
I V Maev   +3 more
doaj  

Collagenous gastritis: A cause of anemia and gastric nodularity in the pediatric population

open access: yesJPGN Reports, EarlyView.
Abstract We present a case series of seven pediatric patients with collagenous gastritis (CG) with the aim of contributing data to existing literature about this rare disease to assist in the understanding and management of these patients. Gross nodularity seen on esophagogastroduodenoscopy and increased subepithelial collagen on biopsy were noted in ...
Megan Emiliani   +2 more
wiley   +1 more source

Benralizumab for anti‐tumor necrosis factor‐associated eosinophilic gastrointestinal disease in a child with ileal Crohn's: A case report

open access: yesJPGN Reports, EarlyView.
Abstract Crohn's disease (CD) and eosinophilic gastrointestinal diseases (EGIDs) are distinct inflammatory entities, but eosinophilic disease may emerge as a paradoxical immune complication of anti–tumor necrosis factor therapy. We report a 12‐year‐old boy with terminal ileal CD who developed severe eosinophilic gastritis and ileitis, peripheral ...
Jonathan Dudzik   +3 more
wiley   +1 more source

Quantitative assay of the suppressive effect of synthetic corticoids in man [PDF]

open access: yes, 1971
Boss, N.   +4 more
core   +1 more source

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