Results 31 to 40 of about 275,378 (374)

Prednisolone Pretreatment Enhances Intermittent Hypoxia-Induced Plasticity in Persons With Chronic Incomplete Spinal Cord Injury

Neurorehabilitation and Neural Repair, 2019
Objective. To test the hypothesis that an anti-inflammatory corticosteroid drug enhances spinal motor plasticity induced by acute intermittent hypoxia (AIH) in persons with chronic incomplete spinal cord injury (iSCI). Methods.
M. Sandhu, E. Gray, M. Kocherginsky, A. Jayaraman, G. Mitchell, W. Rymer   +5 more
semanticscholar   +1 more source

Optimizing the Use of Current Treatments and Emerging Therapeutic Approaches to Achieve Therapeutic Success in Patients with Inflammatory Bowel Disease

Gut and Liver, 2020
The current goal of inflammatory bowel disease (IBD) treatment is a symptom-free everyday life accompanied by mucosal healing with minimal use of corticosteroids.
Hiroshi Nakase
doaj   +1 more source

Brain vitamin D3-auto/paracrine system in relation to structural, neurophysiological, and behavioral disturbances associated with glucocorticoid-induced neurotoxicity

Frontiers in Cellular Neuroscience, 2023
IntroductionVitamin D3 (VD3) is a potent para/autocrine regulator and neurosteroid that can strongly influence nerve cell function and counteract the negative effects of glucocorticoid (GC) therapy.
Olha Lisakovska, Dmytro Labudzynskyi, Anna Khomenko, Dmytro Isaev, Alina Savotchenko, Ludmila Kasatkina, Serhii Savosko, Mykola Veliky, Ihor Shymanskyi   +8 more
doaj   +1 more source

Clinical presentation, diagnostic findings and outcome of dogs with presumptive spinal-only meningoencephalomyelitis of unknown origin [PDF]

, 2017
Objectives: To summarise clinical presentation, diagnostic findings and long-term outcome for dogs clinically diagnosed with meningoencephalomyelitis of unknown origin affecting the spinal cord alone.
Cardy, Coates, Csebi, Da Costa, De Risio, Dewey, Eminaga, Fenn, Granger, Griffin, Meric, Parry, Scott, Tipold   +13 more
core   +2 more sources

Pharmacology and pharmacogenetics of prednisone and prednisolone in patients with nephrotic syndrome

Pediatric nephrology (Berlin, West), 2018
Nephrotic syndrome is one of the most common glomerular disorders in childhood. Glucocorticoids have been the cornerstone of the treatment of childhood nephrotic syndrome for several decades, as the majority of children achieves complete remission after ...
A. Schijvens, R. ter Heine, S. D. de Wildt, M. Schreuder   +3 more
semanticscholar   +1 more source

Validation of the Human Ozone Challenge Model as a Tool for Assessing Anti-Inflammatory Drugs in Early Development [PDF]

, 2005
This study aimed to test the utility of the ozone challenge model for profiling novel compounds designed to reduce airway inflammation. The authors used a randomized, doubledummy, double-blind, placebo-controlled 3-period crossover design alternating ...
Gibson, Anthony, Holz, Olaf, Janicki, Stanislawa, Jörres, Rudolf A., Kanniess, Frank, Magnussen, Helgo, Richter, Kai, Simpson, Kathy J., Tal-Singer, Ruth, Vessey, Rupert S. J.   +9 more
core   +1 more source

Deflazacort versus prednisone/prednisolone for maintaining motor function and delaying loss of ambulation: A post HOC analysis from the ACT DMD trial

Muscle and Nerve, 2018
Introduction: ACT DMD was a 48‐week trial of ataluren for nonsense mutation Duchenne muscular dystrophy (nmDMD). Patients received corticosteroids for ≥6 months at entry and stable regimens throughout study.
P. Shieh, J. Mcintosh, Fengbin Jin, Marcio Souza, G. Elfring, Siva Narayanan, P. Trifillis, S. Peltz, C. McDonald, B. Darras   +9 more
semanticscholar   +1 more source

Brain and Lung Abscesses in a 48-year-old Man with Focal and Segmental Glomerulosclerosis [PDF]

Journal of Clinical and Diagnostic Research, 2015
Focal segmental sclerosis (FSGS) is a common cause of idiopathic nephrotic syndrome in the adult population. A patient aged 48- year-old was admitted for evaluation of azotemia. Renal biopsy showed tip lesion FSGS and acute tubular necrosis.
Ali Momeni, Fereidoon Rahmani, Hamid Nasri   +2 more
doaj   +1 more source

Pharmacokinetic Assessment of Drug‐Drug Interactions of Isavuconazole With the Immunosuppressants Cyclosporine, Mycophenolic Acid, Prednisolone, Sirolimus, and Tacrolimus in Healthy Adults

Clinical pharmacology in drug development, 2016
This report summarizes phase 1 studies that evaluated pharmacokinetic interactions between the novel triazole antifungal agent isavuconazole and the immunosuppressants cyclosporine, mycophenolic acid, prednisolone, sirolimus, and tacrolimus in healthy ...
A. Groll, A. Desai, David Han, Corrie Howieson, Kota Kato, S. Akhtar, D. Kowalski, C. Lademacher, W. Lewis, H. Pearlman, D. Mandarino, T. Yamazaki, R. Townsend   +12 more
semanticscholar   +1 more source

Failure to achieve lupus low disease activity state (LLDAS) six months after diagnosis is associated with early damage accrual in Caucasian patients with systemic lupus erythematosus [PDF]

, 2017
Background: The aim was to assess the attainability and outcome of the lupus low disease activity state (LLDAS) in the early stages of systemic lupus erythematosus (SLE).
CAPPELLAZZO, GIULIA, Cauli, Alberto, Chessa, Elisabetta, Congia, Mattia, Floris, Alberto, Mathieu, Alessandro, Piga, Matteo   +6 more
core   +1 more source