Results 51 to 60 of about 205,860 (279)

Churg-Strauss Syndrome with Necrosis of Toe Tips [PDF]

, 2011
Churg-Strauss syndrome (CSS) is a granulomatous necrotizing vasculitis of unknown etiology associated with bronchial asthma. Despite affecting small to medium-sized vessels, necrosis of the digits due to vasculitis is extremely rare.
Hasegawa, Kenjiro, Ikeda, Genyo, Kanehiro, Arihiko, Kimata, Yoshihiro, Miyahara, Nobuaki, Nojima, Daisuke, Okada, Chiharu, Tanimoto, Mitsune, Tanimoto, Yasushi, Waseda, Koichi   +9 more
core   +1 more source

Nanotherapies for Atherosclerosis: Targeting, Catalysis, and Energy Transduction

Advanced Healthcare Materials, EarlyView.
Atherosclerosis management is hindered by poor drug targeting and plaque heterogeneity. Nanotechnology overcomes these barriers via three core strategies: (1) target‐engineered nanocarriers that achieve lesion‐specific precision via ligand modification, biomimetic camouflage, stimuli‐responsive release, and self‐propelling nanomotors; (2) catalytic ...
Yuqi Yang, Jingguo Qu, Tonghuan Xiao, Xinyang Han, Michael Tin‐Cheung Ying   +4 more
wiley   +1 more source

Vat Polymerization 3D Printing for Controlled Drug Release Applications

Advanced Materials Technologies, EarlyView.
ABSTRACT Vat polymerization (VP) 3D printing, a light‐based additive manufacturing technique, has emerged as a promising technique for fabricating complex drug delivery systems with high precision and spatial resolution. This layer‐by‐layer manufacturing process enables the creation of intricate geometries and customizable architectures, which are ...
Hafiz Busari, O. Thompson Mefford, M. Aaron Vaughn   +2 more
wiley   +1 more source

The efficacy of abiraterone acetate in treating Taiwanese chemo-refractory metastatic castration-resistant prostate cancer patients

Urological Science, 2016
Objective: To evaluate the efficacy of abiraterone acetate in combination with prednisolone in Taiwanese men with metastatic castrate-resistant prostate cancer (mCRPC) who failed docetaxel-based chemotherapy.
Tony Wu, Hsi Chin Wu, Yen Chuan Ou, See-Tong Pang, Yeong-Shiau Pu, Yen-Hwa Chang   +5 more
doaj   +1 more source

A study on the management of corticosteroid side effects in cancer patients [PDF]

, 2015
Background Systemic corticosteroids lead to many adverse effects especially in cancer patients. Preventive measures and treatment options are essential to minimise such side effects.
Fsadni, Clayton John
core  

Overcoming steroid resistance in T cell acute lymphoblastic leukemia [PDF]

, 2016
In a Perspective, Pieter Van Vlierberghe and Steven Goossens discuss Meijerink and colleagues' findings on steroid resistance in pediatric T cell acute lymphoblastic ...
Goossens, Steven, Van Vlierberghe, Pieter   +1 more
core   +3 more sources

Hepatocyte BDNF Acts as a Novel Immune Checkpoint to Restrain TLR4‐Mediated Acute Hepatitis

Advanced Science, EarlyView.
This study identifies hepatocyte‐derived BDNF as an endogenous TLR4 antagonist that alleviates acute hepatitis. BDNF is downregulated in hepatocytes via REST‐mediated transcriptional repression during ALI/ALF. Mechanistically, BDNF binds to TLR4 on macrophages to suppress inflammation.
Weiwei Zhu, Yaqian Cui, Yongqiang Zhou, Yihui Zheng, Lijiang Huang, Leiming Jin, Qianhui Zhang, Pan Chen, Mengsha Lin, Jiaxi Ye, Yongqiang Xiong, Joo Young Huh, Xiang Hu, Xiaokun Li, Wu Luo, Guang Liang   +15 more
wiley   +1 more source

Metabolic stress in patients with acute severe ulcerative colitis - a single-center cohort study

Frontiers in Endocrinology
Background and aimsAcute severe ulcerative colitis (ASUC) is characterized by systemic inflammation, which may initiate an acute-phase response leading to hypercatabolism.
Mathias Redsted, Mathias Redsted, Magnus Grønhøj, Magnus Grønhøj, Louise Dalsgaard Brøchner, Louise Dalsgaard Brøchner, Janne Fassov, Mads Vandsted Svart, Mads Vandsted Svart, Jens Rikardt Andersen, Christian Lodberg Hvas   +10 more
doaj   +1 more source

Preparation and evaluation of conjugate nanogels of glycyl-prednisolone with natural anionic polysaccharides as anti-arthritic delivery systems

Drug Delivery, 2021
Although prednisolone (PD) is used as an anti-arthritis drug due to its rapid and strong anti-inflammatory potential, its frequent and large dosing often brings about adverse effects.
Kohei Mizuno, Yuri Ikeuchi-Takahashi, Yoshiyuki Hattori, Hiraku Onishi   +3 more
doaj   +1 more source

No effect of the turmeric root phenol curcumin on prednisolone-induced glucometabolic perturbations in men with overweight or obesity

Endocrine Connections, 2023
Objectives: Preclinically, curcumin has been shown to protect against glucocorticoid-induced insulin resistance. We evaluated the effect of curcumin administered with prednisolone in healthy overweight or obese men. Methods: In a double-blind, parallel-
Pernille H Hellmann, Jonatan I Bagger, Katrine R Carlander, Katrine B Hansen, Julie L Forman, Joachim Størling, Elizaveta Chabanova, Jens Holst, Tina Vilsbøll, Filip K Knop   +9 more
doaj   +1 more source