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Preeclampsia is a complication of pregnancy in which affected women develop high blood pressure (hypertension); they can also have abnormally high levels of protein in their urine (proteinuria).
R. D’Souza, J. Kingdom
semanticscholar +3 more sources
Preeclampsia accounts for one of the most common documented gestational complications, with a prevalence of approximately 2 to 15% of all pregnancies.
K. Chang, K. Seow, Kuo-Hu Chen
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Background Several recent observational studies have reported that gut microbiota composition is associated with preeclampsia. However, the causal effect of gut microbiota on preeclampsia-eclampsia is unknown. Methods A two-sample Mendelian randomization
Pengsheng Li+8 more
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Genetic Risk Factors Associated With Preeclampsia and Hypertensive Disorders of Pregnancy
Key Points Question What are the genetic risk factors associated with preeclampsia and hypertensive disorders of pregnancy? Findings In this genome-wide association study, 13 novel preeclampsia- or hypertensive pregnancy–associated genetic loci were ...
J. Tyrmi+16 more
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AbstractThe authors review hypertensive disease during pregnancy with an academic and practical view, and using the best evidence available. This disease, which is the most important clinical disease in Brazilian pregnant women, may have its incidence reduced with prevention through the use of calcium and aspirin in pregnant women at risk.
Ramos, José Geraldo Lopes+2 more
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Preeclampsia pathophysiology and adverse outcomes during pregnancy and postpartum
Background Preeclampsia is a disease with far-reaching consequences that extend beyond the immediate postpartum period and have a significant impact later in life. Preeclampsia exerts an effect on most organ systems in the body.
C. Bisson+5 more
semanticscholar +1 more source
Early prediction of preeclampsia in pregnancy with cell-free RNA
Liquid biopsies that measure circulating cell-free RNA (cfRNA) offer an opportunity to study the development of pregnancy-related complications in a non-invasive manner and to bridge gaps in clinical care1–4.
M. Moufarrej+16 more
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Gut Dysbiosis Promotes Preeclampsia by Regulating Macrophages and Trophoblasts
Background: Preeclampsia is one of the leading causes of maternal and perinatal morbidity and is characterized by hypertension, inflammation, and placental dysfunction. Gut microbiota plays key roles in inflammation and hypertension.
Jiajia Jin+13 more
semanticscholar +1 more source
Preeclampsia Prevalence, Risk Factors, and Pregnancy Outcomes in Sweden and China
This cross-sectional study compared preeclampsia prevalence, risk factors, and pregnancy outcomes between the Swedish and Chinese populations.
Yingying Yang+5 more
semanticscholar +1 more source
Prevention of Preeclampsia [PDF]
Preeclampsia (PE) affects around 2–5% of pregnant women. It is a major cause of maternal and perinatal morbidity and mortality. In an attempt to prevent preeclampsia, many strategies based on antenatal care, change in lifestyle, nutritional supplementation, and drugs have been studied.
Fabricio da Silva Costa+5 more
openaire +4 more sources