Differential expression of microRNA-206 and its target genes in pre-eclampsia [PDF]
Objectives: Pre-eclampsia is a multi-system disease that significantly contributes to maternal and fetal morbidity and mortality. In this study, we used a non-biased microarray approach to identify novel circulating miRNAs in maternal plasma that may be ...
Akehurst, Christine +12 more
core +1 more source
Maternal Cardiovascular Impairment in Pregnancies Complicated by Severe Fetal Growth Restriction [PDF]
—Fetal growth restriction and preeclampsia are both conditions of placental etiology and associated to increased risk for the long-term development of cardiovascular disease in the mother. At presentation, preeclampsia is associated with maternal global
Liberati, M +3 more
core +1 more source
Metabolomics application in maternal-fetal medicine [PDF]
Metabolomics in maternal-fetal medicine is still an "embryonic" science. However, there is already an increasing interest in metabolome of normal and complicated pregnancies, and neonatal outcomes. Tissues used for metabolomics interrogations of pregnant
Atzori, L +4 more
core +4 more sources
Regulation of stanniocalcin-1 secretion by BeWo cells and first trimester human placental tissue from normal pregnancies and those at increased risk of developing preeclampsia. [PDF]
Stanniocalcin-1 (STC-1) is a multi-functional glycosylated peptide present in the plasma of healthy women postpartum and increased further in pregnancies complicated by preeclampsia. Although the STC-1 gene is expressed by the placenta what regulates its
Asma Khalil +13 more
core +1 more source
Neutrophil count is a useful marker to predict the severity of preeclampsia
Background At present, pre-eclampsia is a growing concern and still a diagnostic challenge for obstetricians. Aims This study aimed to evaluate whether the relationship of second trimester of pregnancy neutrophil count differed among pregnancies with ...
Miao Liu +13 more
doaj +1 more source
Background: Preeclampsia and eclampsia are vital causes of maternal morbidity and mortality around the world. In Egypt, it complicates about 6%-8% of all pregnancies and can reach up to 15% in referral centers like university hospitals.
Rania Abd El Hakeem Ameen +2 more
doaj +1 more source
Function of survivin in trophoblastic cells of the placenta [PDF]
Background: Preeclampsia is one of the leading causes of maternal and perinatal mortality and morbidity worldwide and its pathogenesis is not totally understood.
Friemel, Alexandra +5 more
core +3 more sources
Trophoblast lineage-specific differentiation and associated alterations in preeclampsia and fetal growth restriction. [PDF]
The human placenta is a poorly-understood organ, but one that is critical for proper development and growth of the fetus in-utero. The epithelial cell type that contributes to primary placental functions is called "trophoblast," including two main ...
Farah, Omar +3 more
core +2 more sources
Las distintas manifestaciones de la toxicosis gravídica que precede a la máxima complicación de ella, conocida con el nombre de eclampsia se ha denominado Preeclampsia. Este término comprende el conocido cuadro de las albuminurias gravidicas. primer eslabón de la cadena tóxica y la entidad de que nos ocupamos, conocida con el nombre Eclampsismo de ...
Rafael Peralta +2 more
openaire +3 more sources
Cluster analysis to estimate the risk of preeclampsia in the high-risk Prediction and Prevention of Preeclampsia and Intrauterine Growth Restriction (PREDO) study. [PDF]
OBJECTIVES:Preeclampsia is divided into early-onset (delivery before 34 weeks of gestation) and late-onset (delivery at or after 34 weeks) subtypes, which may rise from different etiopathogenic backgrounds.
Pia M Villa +11 more
doaj +1 more source

