Results 91 to 100 of about 1,368,837 (297)

The development and preliminary validation of a Preference-Based Stroke Index (PBSI)

open access: yesHealth and Quality of Life Outcomes, 2003
Background Health-related quality of life (HRQL) is a key issue in disabling conditions like stroke. Unfortunately, HRQL is often difficult to quantify in a comprehensive measure that can be used in cost analyses. Preference-based HRQL measures meet this
Clarke Ann E   +3 more
doaj   +1 more source

PERFORMANCE EVALUATION ON QUALITY OF ASIAN AIRLINES WEBSITES – AN AHP PPROACH [PDF]

open access: yes, 2009
In recent years, many people have devoted their efforts to the issue of quality of Web site. The concept of quality is consisting of many criteria: quality of service perspective, a user perspective, a content perspective or indeed a usability ...
Jati, Handaru
core  

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

A measure of rationality and welfare [PDF]

open access: yes
There is evidence showing that individual behavior often deviates from the classical principle of maximization. This evidence raises at least two important questions: (i) how severe the deviations are and (ii) which method is the best for extracting ...
Jose Apesteguia, Miguel Angel Ballester
core  

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Community Perceptions of Unmeasured Quality Improvement in Goods and Services [PDF]

open access: yes
Because of the costs involved in such exercises, current productivity measures do not necessarily fully take into account changes in the quality of goods and services over time.
Ian Black
core  

Measuring consensus in a preference-approval context [PDF]

open access: yes, 2012
We consider measuring the degree of homogeneity for preference-approval profiles which include the approval information for the alternatives as well as the rankings of them.
Erdamar, Bora   +3 more
core   +2 more sources

Fluorescence-based incision assay for human XPF-ERCC1 activity identifies important elements of DNA junction recognition [PDF]

open access: yes, 2012
The structure-specific endonuclease activity of the human XPF–ERCC1 complex is essential for a number of DNA processing mechanisms that help to maintain genomic integrity.
Bowles, M.   +5 more
core   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Measurement-Theoretic Foundation of Preference-Based Dyadic Deontic Logic [PDF]

open access: yes, 2009
The contemporary development of deontic logic since von Wright has been based on the study of the analogies between normative and alethic modalities. The weakest deontic logic called standard deontic logic (SDL) is the modal system of type KD. Jones and Sergot argued that contrary-to-duty (CTD) reasoning was necessary to represent the legal codes in ...
openaire   +1 more source

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