Results 111 to 120 of about 25,563,837 (296)
Developing a preference-based measure for weight-specific health-related quality of life in adolescence: the WAItE UK valuation study protocol. [PDF]
BMJ Open, 2021 Robinson T, Hill S, Oluboyede Y.
europepmc +1 more source
In search of a preferred preference elicitation method: A test of the internal consistency of choice and matching tasks [PDF]
The numerous reports on preference reversals in preference elicitations pose a great challenge to empirical economics. Many studies have found that different procedures may generate substantially different preferences.
Attema, Arthur, Brouwer, Werner
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Artificial molecular machines and motors—Design and control of nanoscale motion
FEBS Letters, EarlyView.Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley +1 more source
Validity and Interpretation of Preference-Based Measures of Health-Related Quality of Life
Medical Care, 2000 Utilities are numeric measurements that reflect an individual's beliefs about the desirableness of a health condition, willingness to take risks to gain health benefits, and preferences for time. This report discusses the approaches to assess and compare the validity of methods used to assign utilities for cost-utility analysis.
L, Lenert, R M, Kaplan
openaire +2 more sources
Valuation of the Child Health Utility Index 9D (CHU9D) [PDF]
Objectives The aim of this study was to test the feasibility of estimating preference weights for all health states defined by the Child Health Utility 9D (CHU9D), a new generic measure of health related quality of life for children.
Stevens, K
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FEBS Letters, EarlyView.Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise +5 more
wiley +1 more source
Improving the measurement of QALYs in dementia: developing patient- and carer-reported health state classification systems using Rasch analysis [PDF]
Objectives: Cost-utility analysis is increasingly used to inform resource allocation. This requires a means of valuing health states before and after intervention. Although generic measures are typically used to generate values, these do not perform well
Knapp, M +9 more
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FEBS Letters, EarlyView.Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana +3 more
wiley +1 more source
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
A comparison of United States and United Kingdom EQ-5D health states valuations using a nonparametric Bayesian method [PDF]
Few studies have compared preference values of health states obtained in different countries. This paper applies a nonparametric model to estimate and compare EQ-5D health state valuation data obtained from two countries using Bayesian methods.
Kharroubi, SA, Brazier, JE, O'Hagan, A
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