Results 111 to 120 of about 1,368,837 (297)

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

FEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz, Bruna Abreu, Cindy Mendes, Catarina Freitas‐Dias, Filipe Gonçalves, Fernanda Silva, José Ramalho, Saudade André, Vasco D. B. Bonifácio, Jacinta Serpa   +9 more
wiley   +1 more source

Complexity and Simplification in Understanding Travel Preferences Among Tourists

Frontiers in Psychology, 2019
Travel preferences are complex phenomena, and thus cumbersome to deal with in full width in diagnostic and strategic planning processes. The aim of the present investigation was to explore to what extent individual preferences can be simplified into ...
Torvald Øgaard, Rouven Doran, Svein Larsen, Katharina Wolff   +3 more
doaj   +1 more source

Developing a preference-based measure for weight-specific health-related quality of life in adolescence: the WAItE UK valuation study protocol. [PDF]

BMJ Open, 2021
Robinson T, Hill S, Oluboyede Y.
europepmc   +1 more source

Antibiofilm activity of a chionodracine‐derived peptide by NMR‐based metabolomics of cell‐free supernatant of Acinetobacter baumannii clinical strains

FEBS Open Bio, EarlyView.
KHS‐Cnd peptide is able to impair biofilm formation and disaggregate mature biofilms in Acinetobacter baumannii clinical isolates. Differences in extracellular metabolites reflect changes in biofilm metabolism due to KHS‐Cnd treatment. Among the differentially represented extracellular metabolites upon KHS‐Cnd treatment, the significantly altered ...
Fernando Porcelli, Enrico Landi, Francesco Maiurano, Irene Paris, Rosanna Papa, Marco Artini, Laura Selan, Stefano Borocci, Francesco Buonocore, Esther Imperlini   +9 more
wiley   +1 more source

An assessment of fertilizer spraying drones based on hesitancy fuzzy similarity measures for sustainable green development

AIP Advances
This research proposes a new similarity measure on hesitancy fuzzy graphs. The similarity measures are crucial concepts to explore the closeness between fuzzy graphs.
Rajagopal Reddy N, S. Sharief Basha, Obbu Ramesh, Nainaru Tarakaramu, Hijaz Ahmad, Sameh Askar, Ramalingam Sivajothi   +6 more
doaj   +1 more source

Shared Decision-Making and Patient Satisfaction in Japanese Rheumatoid Arthritis Patients: A New “Preference Fit” Framework for Treatment Assessment

Rheumatology and Therapy, 2019
Introduction We have developed a new framework to assess shared decision-making (SDM) as a tool to improve patient satisfaction. This framework is based on a “preference fit” index that relates SDM to patient treatment preferences and patient ...
Jörg Mahlich, Ulrike Schaede, Rosarin Sruamsiri   +2 more
doaj   +1 more source

A Geometric Measure for the Violation of Utility Maximization [PDF]

Revealed Preference offers nonparametric tests for whether consumption observations can be rationalized by a utility function. If a consumer is inconsistent with GARP, we might need a measure for the severity of inconsistency.
Jan Heufer
core  

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

FEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig, Swanhild Lohse, Sara Elahi, Nils Hartmann, Stefanie Deckert, Shutian Si, Alexander Desuki, Anja Harder   +7 more
wiley   +1 more source

TMC4 localizes to multiple taste cell types in the mouse taste papillae

FEBS Open Bio, EarlyView.
Transmembrane channel‐like 4 (TMC4), a voltage‐dependent chloride channel, plays a critical role in amiloride‐insensitive salty taste transduction. TMC4 is broadly expressed in all mature taste cell types, suggesting a possible involvement of multiple cell types in this pathway.
Momo Murata, Yoshikazu Saito, Yoichi Kasahara, Wataru Fujii, Takumi Misaka, Tomiko Asakura, Masataka Narukawa   +6 more
wiley   +1 more source

Using Rasch analysis to form plausible health states amenable to valuation: the development of CORE-6D from CORE-OM in order to elicit preferences for common mental health problems

, 2001
Purpose: To describe a new approach for deriving a preference-based index from a condition specific measure that uses Rasch analysis to develop health states.
Mavranezouli, I., Brazier, J.E., Young, T.A., Barkham, M.   +3 more
core