Results 81 to 90 of about 1,233,746 (351)

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Can intergenerational equity be operationalized? [PDF]

open access: yes
A long Utilitarian tradition has the ideal of equal regard for all individuals, both those now living and those yet to be born. The literature formalizes this ideal as asking for a preference relation on the space of infinite utility streams that is ...
Zame, William R.
core   +1 more source

Flexible Level-1 Consensus Ensuring Stable Social Choice: Analysis and Algorithms

open access: yes, 2017
Level-1 Consensus is a property of a preference-profile. Intuitively, it means that there exists a preference relation which induces an ordering of all other preferences such that frequent preferences are those that are more similar to it.
Nitzan, Mor   +2 more
core   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

A Novel Approach to Decision-Making with Pythagorean Fuzzy Information

open access: yesMathematics, 2018
A Pythagorean fuzzy set (PFS) is a powerful tool for depicting fuzziness and uncertainty. This model is more flexible and practical as compared to an intuitionistic fuzzy model. This paper proposes a new graph, called Pythagorean fuzzy graph (PFG).
Sumera Naz   +2 more
doaj   +1 more source

A utility representation theorem with weaker continuity condition [PDF]

open access: yes
We prove that a preference relation which is continuous on every straight line has a utility representation if its domain is a convex subset of a finite dimensional vector space.
Tomoki Inoue
core  

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

Group Decision-Making Model With Hesitant Multiplicative Preference Relations Based on Regression Method and Feedback Mechanism

open access: yesIEEE Access, 2018
The hesitant multiplicative preference relation (HMPR) was initially put forward in 2013. Utilizing the HMPR, the decision makers can give some possible preference values from the Saaty's 1-9 scale for pairwise comparisons over alternatives.
Mingwei Lin   +3 more
doaj   +1 more source

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