Results 81 to 90 of about 155,233 (267)
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Preferences in Temporal Relational Databases
IEEE AccessDespite the huge amount of work devoted to the treatment of time within the relational context, some relevant phenomena remain to be fully addressed. We focus on one of them, i.e., temporal indeterminacy with preferences. In several domains (e.g., workflows, guidelines) and tasks (e.g., planning, scheduling), the exact time of occurrence of facts is ...
Luca Anselma, Paolo Terenziani
openaire +5 more sources
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Continuity of Preference Relations for Separable Topologies [PDF]
International Economic Review, 1988 A preference relation is shown to be continuous w.r.t. some separable topology, if and only if the preference relation is embeddable in the set \({\mathbb{R}}\times \{0,1\}\) endowed with the lexicographic ordering. This result is used as the starting point to obtain alternative proofs for some representation theorems of consumer demand theory.
openaire +4 more sources
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Preferences Relations and Consumer Theory
, 2017 8 pages, no figures, and no ...
Ferreira, M. A. M., Filipe, J. A.
openaire +4 more sources
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Existtence of smooth uttilities on Bannach lattices
Rect@, 1998 In this paper we consider consumption sets of an infinite dimensional commodity space. Our work deals with the representability of a preference relation by differentiable utility functions, that is, we obtain sufficient conditions for the existence of ...
Vázquez Pampín, C., Besada Morais, M.
doaj
On quasistability radius of a vector trajectorial problem with a principle of optimality generalizing Pareto and lexicographic principles [PDF]
Computer Science Journal of Moldova, 2005 A multicriterion linear combinatorial problem with a parametric principle of optimality is considered. This principle is defined by a partitioning of partial criteria onto Pareto preference relation groups within each group and the lexicographic ...
Sergey E. Bukhtoyarov +1 more
doaj