Results 121 to 130 of about 2,501,837 (301)
Is more health always better? Exploring public preferences that violate monotonicity [PDF]
Abásolo and Tsuchiya (2004a) report on an empirical study to elicit public preferences regarding the efficiency-equality trade-off in health, where the majority of respondents violated monotonicity.
Abásolo, I., Tsuchiya, A.
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Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao +3 more
wiley +1 more source
Cette note est consacrée à la question:Quelle restriction impose-t-on en faisant l'hypothèse qu'un profil de préférences est euclidien en dimension d ?
Anna Bogomolnaïa +1 more
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Digital twins to accelerate target identification and drug development for immune‐mediated disorders
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley +1 more source
PREFERENCES OF POTENTIAL APPLICANTS FOR UNIVERSITY EDUCATION AND THE “LEARNING ECONOMY”
In the current postmodern society, knowledge is still more important. Also corresponding with this fact are the development theories which have been developed from the theory of learning organisation, the theory of learning regions to the relatively new ...
Jaku Husák, Markéta Volkánová
doaj
Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková +3 more
wiley +1 more source
BACKGROUND: Obesity has become a pandemic, with more than a billion people affected worldwide. During the past two decades, the prevalence of obesity in children has risen greatly throughout the entire world.
Michal Kudláček, Lisa Carla James
doaj
Distinguishing Social Preferences from Preferences for Altruism [PDF]
We report a laboratory experiment that enables us to distinguish preferences for altruism (concerning tradeoffs between own payoffs and the payoffs of others) from social preferences (concerning tradeoffs between the payoffs of others).
Daniel Markovits +2 more
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Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke +4 more
wiley +1 more source
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani +6 more
wiley +1 more source

